ReviewFrontiers in bioengineering and biotechnology2022
Role of fibroblasts in wound healing and tissue remodeling on Earth and in space.
Review in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 169 papers.
What it found
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Who cites it
169 citing papers in PubMed.
- Article
- The potential of plant-derived exosome-like nanovesicles fromFuture science OA · 2026Article
- Inflammasome-derived biomarkers in wound healing: linking tissue repair, chronic inflammation, fibrosis, and precision therapeutics.Molecular biology reports · 2026Review
- Probiotics and Extracellular Vesicles as Redox Modulators in Wound Healing: From Microbial Therapeutics to Engineered Nanotherapeutic Strategies.Antioxidants (Basel, Switzerland) · 2026Review
- Photothermal interaction of a 1927 nm Thulium laser with MatriDerm: an in vitro study.Lasers in medical science · 2026Article
- Multifunctional Silk Fibroin-Curcuminoid Films Combining Regenerative and Antioxidant Properties with pH Sensing for Wound Dressing Applications.Biomimetics (Basel, Switzerland) · 2026Article
- Healing the Sole: Combining Natural Plant Extracts and Conventional Drugs in Wound Delivery Systems for Diabetic Foot Ulcer Treatment.International journal of molecular sciences · 2026Review
- Behavioral and Functional Profiling ofbioRxiv : the preprint server for biology · 2026Article
- Fibrin-Based Biomaterials in Wound Healing and Soft Tissue Regeneration: Biological Mechanisms and Clinical Applications.Gels (Basel, Switzerland) · 2026Review
- Article
- Mechanisms and Clinical Manifestations of Age-Related Impairment in Wound Healing.International wound journal · 2026Review
- Untreated Rosehip Powder/Poly(Lactic Acid)/Poly(3-Hydroxybutyrate-Co-4-Hydroxybutyrate) Electrospun Mats for Wound Dressing Applications.Biopolymers · 2026Article
- Bioprinted human skin equivalent for evaluating non-invasive monopolar radiofrequency treatment: a novel approach.Lasers in medical science · 2026Article
- Characterizing pancreatic cancer-associated fibroblast heterogeneity in vascular microphysiological systems.Angiogenesis · 2026Article
- Functional Hybrid Wound Scaffolds for Controlled Drug Delivery and Smart Wound Management: A Decade of Progress.AAPS PharmSciTech · 2026Review
- Targeting Biofilms in Chronic Wounds: Emerging Strategies with Antimicrobial Nanocomposites.Journal of functional biomaterials · 2026Review
- Green Synthesis of Iron Oxide-Chitosan-Glutathione Nanosystem for Wound Healing Enhancement.Cell biochemistry and biophysics · 2026Article
- ECM-Stiffness Mediated Persistent Fibroblast Activation Requires Integrin and Formin Dependent Chromatin Remodeling.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Isolating and Validating Fibroblast-like Cells from the Skeletal Muscle of the Siamese Crocodile (Veterinary sciences · 2026Article
- Optimisation of low-level light therapy (lllt) parameters and evaluation of its immunomodulatory effect on fibroblasts.Lasers in medical science · 2026Article
109 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wound healing (WH) and the role fibroblasts play in the process, as well as healing impairment and fibroblast dysfunction, have been thoroughly reviewed by other authors. We treat these topics briefly, with the only aim of contextualizing the true focus of this review, namely, the microgravity-induced changes in fibroblast functions involved in WH. Microgravity is a condition typical of spaceflight. Studying its possible effects on fibroblasts and WH is useful not only for the safety of astronauts who will face future interplanetary space missions, but also to help improve the management of WH impairment on Earth. The interesting similarity between microgravity-induced alterations of fibroblast behavior and fibroblast dysfunction in WH impairment on Earth is highlighted. The possibility of using microgravity-exposed fibroblasts and WH in space as models of healing impairment on Earth is suggested. The gaps in knowledge on fibroblast functions in WH are analyzed. The contribution that studies on fibroblast behavior in weightlessness can make to fill these gaps and, consequently, improve therapeutic strategies is considered.
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