Evidence map›Paper›PMID 36267444›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Decellularized esophageal tubular scaffold microperforated by quantum molecular resonance technology and seeded with mesenchymal stromal cells for tissue engineering esophageal regeneration.

Maurizio Marzaro, Gianantonio Pozzato, Stefano Tedesco, Mattia Algeri, Alessandro Pozzato, Luigi Tomao, Ilaria Montano, Filippo Torroni, Valerio Balassone, Anna Chiara Iolanda Contini and 16 more

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Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Maurizio MarzaroPediatric Surgery Department AULSS2 Treviso, Treviso, Italy.
Gianantonio PozzatoTelea Electronic Engineering Vicenza, Vicenz, Italy.
Stefano TedescoTelea Biotech Vicenza, Vicenz, Italy.
Mattia AlgeriDepartment of Pediatric Onco-Hematology and Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Alessandro PozzatoTelea Electronic Engineering Vicenza, Vicenz, Italy.
Luigi TomaoDepartment of Pediatric Onco-Hematology and Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Ilaria MontanoDepartment of Pediatric Onco-Hematology and Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Filippo TorroniDigestive Endoscopy and Surgical Unit, Bambino Gesù Children's Hospital, Rome, Italy.
Valerio BalassoneDigestive Endoscopy and Surgical Unit, Bambino Gesù Children's Hospital, Rome, Italy.
Anna Chiara Iolanda ContiniDigestive Endoscopy and Surgical Unit, Bambino Gesù Children's Hospital, Rome, Italy.
Luciano GuerraDigestive Endoscopy and Surgical Unit, Bambino Gesù Children's Hospital, Rome, Italy.
Tommaso D'AngeloDigestive Endoscopy and Surgical Unit, Bambino Gesù Children's Hospital, Rome, Italy.
Giovanni Federici di AbriolaDigestive Endoscopy and Surgical Unit, Bambino Gesù Children's Hospital, Rome, Italy.
Lorenzo LupoiCen.Ri.S. Policlinico Gemelli UNICATT Rome, Rome, Italy.
Maria Emiliana CaristoCen.Ri.S. Policlinico Gemelli UNICATT Rome, Rome, Italy.
Ivo BoškoskiFondazione Policlinico Universitario Agostino Gemelli IRCCS, Digestive Endoscopy Unit, Rome, Italy.
Guido CostamagnaFondazione Policlinico Universitario Agostino Gemelli IRCCS, Digestive Endoscopy Unit, Rome, Italy.
Paola FrancalanciPathology Department Bambino Gesù Children's Hospital, Rome, Italy.
Giuseppe AstoriAdvanced Cellular Therapy Laboratory, Haematology Unit, San Bortolo Hospital, Vicenza, Italy.
Angela BozzaAdvanced Cellular Therapy Laboratory, Haematology Unit, San Bortolo Hospital, Vicenza, Italy.
Andrea BagnoDepartment of Industrial Engineering, University of Padova, Padova, Italy.
Martina TodescoDepartment of Industrial Engineering, University of Padova, Padova, Italy.
Emanuele TrovalusciPediatric Surgery Department AULSS2 Treviso, University of Padova, Padova, Italy.
Luigi Dall' OglioDigestive Endoscopy and Surgical Unit, Bambino Gesù Children's Hospital, Rome, Italy.
Franco LocatelliDepartment of Pediatric Onco-Hematology and Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Tamara CaldaroDigestive Endoscopy and Surgical Unit, Bambino Gesù Children's Hospital, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current surgical options for patients requiring esophageal replacement suffer from several limitations and do not assure a satisfactory quality of life. Tissue engineering techniques for the creation of customized "self-developing" esophageal substitutes, which are obtained by seeding autologous cells on artificial or natural scaffolds, allow simplifying surgical procedures and achieving good clinical outcomes. In this context, an appealing approach is based on the exploitation of decellularized tissues as biological matrices to be colonized by the appropriate cell types to regenerate the desired organs. With specific regard to the esophagus, the presence of a thick connective texture in the decellularized scaffold hampers an adequate penetration and spatial distribution of cells. In the present work, the Quantum Molecular Resonance

Indexed as

esophagusmesenchymal stromal cellsquantum molecular resonancescaffoldtissue engineering

Identifiers

PMID36267444
PMCPMC9576845

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.