Evidence map›Paper›PMID 36267409›Full record

SynthesisFrontiers in genetics2022

Progress in research on the role of exosomal miRNAs in the diagnosis and treatment of cardiovascular diseases.

Jinyu Xu, Weitie Wang, Yong Wang, Zhicheng Zhu, Dan Li, Tiance Wang, Kexiang Liu

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jinyu XuDepartment of Cardiovascular Surgery, The Second Hospital of Jilin University, Changchun, China.
Weitie WangDepartment of Cardiovascular Surgery, The Second Hospital of Jilin University, Changchun, China.
Yong WangDepartment of Cardiovascular Surgery, The Second Hospital of Jilin University, Changchun, China.
Zhicheng ZhuDepartment of Cardiovascular Surgery, The Second Hospital of Jilin University, Changchun, China.
Dan LiDepartment of Cardiovascular Surgery, The Second Hospital of Jilin University, Changchun, China.
Tiance WangDepartment of Cardiovascular Surgery, The Second Hospital of Jilin University, Changchun, China.
Kexiang LiuDepartment of Cardiovascular Surgery, The Second Hospital of Jilin University, Changchun, China.
Second Affiliated Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases are the most common diseases threatening the health of the elderly, and the incidence and mortality rates associated with cardiovascular diseases remain high and are increasing gradually. Studies on the treatment and prevention of cardiovascular diseases are underway. Currently, several research groups are studying the role of exosomes and biomolecules incorporated by exosomes in the prevention, diagnosis, and treatment of clinical diseases, including cardiovascular diseases. Now, based on the results of published studies, this review discusses the characteristics, separation, extraction, and identification of exosomes, specifically the role of exosomal miRNAs in atherosclerosis, myocardial injury and infarction, heart failure, aortic dissection, myocardial fibrosis, ischemic reperfusion, atrial fibrillation, and other diseases. We believe that the observations noted in this article will aid in the prevention, diagnosis, and treatment of cardiovascular diseases.

Indexed as

cardiocardiovascularexosomesmiRNAtreatment

Identifiers

PMID36267409
PMCPMC9577319
OpenAlexW4301398786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.