Evidence map›Paper›PMID 36267293›Full record

ArticleFrontiers in pharmacology2022

Novel saccharin analogs as promising antibacterial and anticancer agents: synthesis, DFT, POM analysis, molecular docking, molecular dynamic simulations, and cell-based assay.

Magda H Abdellattif, Ahmed Elkamhawy, Mohamed Hagar, Taibi Ben Hadda, Wesam S Shehab, Wael Mansy, Amany Belal, M M H Arief, Mostafa A Hussien

Abstract read
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Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Magda H AbdellattifDepartment of Chemistry, College of Science, Taif University, Taif, Saudi Arabia.
Ahmed ElkamhawyCollege of Pharmacy, Dongguk University-Seoul, Goyang, South Korea.
Mohamed HagarChemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt.
Taibi Ben HaddaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Wesam S ShehabDepartment of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt.
Wael MansyDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Amany BelalDepartment of Pharmaceutical Chemistry, College of Pharmacy Taif University, Taif, Saudi Arabia.
M M H AriefDepartment of Chemistry, Faculty of Science, Benha University, Benha, Egypt.
Mostafa A HussienDepartment of Chemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Saccharine is a pharmacologically significant active scaffold for various biological activities, including antibacterial and anticancer activities. Herein, saccharinyl hydrazide (

Indexed as

DFTdockingMDpharmacophore sitesPOM analysessaccharinyl hydrazide

Identifiers

PMID36267293
PMCPMC9577234

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.