Evidence map›Paper›PMID 36267041›Full record

ArticleThoracic cancer2022

Intraoperative ultrasound: "Alternative eye" in lymph nodal dissection in non-small cell lung cancer.

Gaetana Messina, Mary Bove, Antonio Noro, Giorgia Opromolla, Giovanni Natale, Rosa Mirra, Francesca Capasso, Davide Gerardo Pica, Vincenzo Di Filippo, Mario Pirozzi and 9 more

Open access · goldAbstract read
In one paragraph

Article in Thoracic cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Global trends and academic landscapes of ultrasound applications in lung cancer research: a bibliometric analysis (2000-2024).Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 1 country.

Gaetana MessinaThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Napoli, Italy.ORCID 0000-0001-5129-7201
Mary BoveThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Napoli, Italy.
Antonio NoroThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Napoli, Italy.
Giorgia OpromollaThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Napoli, Italy.
Giovanni NataleThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Napoli, Italy.
Rosa MirraThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Napoli, Italy.
Francesca CapassoThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Napoli, Italy.
Davide Gerardo PicaThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Napoli, Italy.
Vincenzo Di FilippoThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Napoli, Italy.
Mario PirozziOncology, Department of Precision Medicine, Università della Campania "L. Vanvitelli", Naples, Italy.
Marianna CaterinoOncology, Department of Precision Medicine, Università della Campania "L. Vanvitelli", Naples, Italy.
Sergio FacchiniOncology, Department of Precision Medicine, Università della Campania "L. Vanvitelli", Naples, Italy.
Alessia ZottaOncology, Department of Precision Medicine, Università della Campania "L. Vanvitelli", Naples, Italy.
Rita PolitoNutrition Science, University of Foggia, Foggia, Italy.
Giovanni VicidominiThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Napoli, Italy.
Mario SantiniThoracic Surgery Unit, Università degli Studi della Campania "Luigi Vanvitelli", Napoli, Italy.
Alfonso FiorelliOncology, Department of Precision Medicine, Università della Campania "L. Vanvitelli", Naples, Italy.ORCID 0000-0002-0628-613X
Fortunato CiardielloOncology, Department of Precision Medicine, Università della Campania "L. Vanvitelli", Naples, Italy.
Morena FasanoOncology, Department of Precision Medicine, Università della Campania "L. Vanvitelli", Naples, Italy.
University of Campania "Luigi Vanvitelli" · ITUniversity of Foggia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionStaging of the mediastinum lymph nodes involvement in patients with non-small cell lung cancer (NSCLC) is an important prognostic factor determining the most appropriate multimodality treatment plan. The objective of this study is to assess ultrasound characteristics of mediastinal lymph nodes metastasis and effectiveness of intraoperative ultrasound-guided mediastinal nodal dissection in patients with resected NSCLC. MATERIALS AND

methodsAll patients undergoing video-assisted thoracoscopic surgery lobectomy and pulmonary lymphadenectomy from November 2020 to March 2022 at the thoracic surgery department of the Vanvitelli University of Naples underwent intraoperative ultrasound-guided mediastinal lymph nodal dissection.

resultsThis study evaluates whether individual B-mode features and a compounding thereof can be used to accurately and reproducibly predict lymph node malignancy. DISCUSSION: Intraoperative ultrasound, during systematic mediastinal lymph node dissection, is helpful in preventing lesion to mediastinal structures. Pathological nodal sonographic characteristics are round shape, short-axis diameter, echogenicity, margin, the absence or presence of coagulation necrosis sign, and the absence or presence of central hilar structure, increased color Doppler flow, the absence or presence of calcification, and nodal conglomeration. Operating time was not substantially prolonged. The procedure is simple, safe and highly accurate.

conclusionsUltrasonic techniques allow surgeons to detect the relationship between lymph nodes and surrounding large blood vessels during biopsy, improving the safety and simplicity of the operation, increasing the number of harvested lymph nodes, and reducing the risk of intraoperative injury; it is a fast, easily reproducible, and inexpensive method.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsHumansLymphatic MetastasisLymph Node ExcisionMediastinumNeoplasm StagingRetrospective StudiesUltrasonographylymph nodesmediastinumnon-small cell lung cancerstadiationultrasound

Identifiers

PMID36267041
PMCPMC9715883
OpenAlexW4306970594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.