ArticleJournal of translational medicine2022
Combined association of triglyceride-glucose index and systolic blood pressure with all-cause and cardiovascular mortality among the general population.
Article in Journal of translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Predictive significance of triglyceride-glucose index in forecasting adverse cardiovascular events among Type 2 diabetes mellitus patients with co-existing metabolic dysfunction-associated steatotic liver disease (MASLD): evidence from two cohort studies.Cardiovascular diabetology · 2026Article
- Insulin Resistance and Atherogenic Dyslipidemia Drive Cardiac Remodeling and Cardiovascular Events After Kidney Transplantation.Journal of clinical medicine · 2026Article
- The relationship between IGF-1 and cardiovascular diseases and the potential mediating role of TyG-related index: evidence from a cohort study.BMC cardiovascular disorders · 2026Article
- Blood pressure-stratified associations of the atherogenic index of plasma with all-cause mortality: a 10-year rural cohort study in China.Frontiers in cardiovascular medicine · 2026Article
- Development and validation of a cross-sectional risk screening nomogram for carotid plaque based on routine health examination data and the triglyceride-glucose-waist-to-hip ratio.Frontiers in endocrinology · 2026Article
- Association Between Triglyceride-Glucose Index, Blood Pressure Status, and Coronary Heart Disease Risk Among Chinese Adults With Disabilities: 10-Year Disability Health Survey Cohort Study.JMIR public health and surveillance · 2025Article
- Association between TG/HDL-C ratio or triglyceride-glucose index and mean arterial pressure in patients with myocardial infarction.Scientific reports · 2025Article
- Interaction and combined effect of triglyceride-glucose index and hypertension on type 2 diabetes individuals' peripheral arterial disease risk.Acta diabetologica · 2025Article
- Nonlinear association between triglyceride-glucose index and 28-day mortality in intensive care units: a multi-center retrospective cohort study.Frontiers in endocrinology · 2025Article
- The prognostic association of triglyceride-glucose index and its derived indicators with stable coronary artery disease patients undergoing percutaneous coronary intervention.Frontiers in endocrinology · 2025Article
- Association between triglyceride-glucose index and all-cause mortality in patients underwent transcatheter aortic valve replacement.BMC cardiovascular disorders · 2024Article
- Triglyceride-Glucose Index as Predictor for Hypertension, CHD and STROKE Risk among Non-Diabetic Patients: A NHANES Cross-Sectional Study 2001-2020.Journal of epidemiology and global health · 2024Article
- Interacting and joint effects of triglyceride-glucose index and blood pressure on cardiovascular diseases risk: a prospective cohort study.Diabetology & metabolic syndrome · 2024Article
- Association of the triglyceride-glucose index with all-cause and cause-specific mortality: a population-based cohort study of 3.5 million adults in China.The Lancet regional health. Western Pacific · 2024Article
- Systolic blood pressure status modifies the associations between the triglyceride-glucose index and incident cardiovascular disease: a national cohort study in China.Cardiovascular diabetology · 2024Article
- Association of triglyceride glucose-body mass index and hemoglobin glycation index with heart failure prevalence in hypertensive populations: a study across different glucose metabolism status.Lipids in health and disease · 2024Article
- Association between triglyceride glucose index and all-cause mortality in patients with cerebrovascular disease: a retrospective study.Diabetology & metabolic syndrome · 2024Article
- The associations of the triglyceride-glucose index and its combination with blood pressure on cardiovascular and all-cause mortality in hypertension: a national study.Frontiers in endocrinology · 2024Article
- Influence of renal function on the ability of TyG Index to predict all-cause mortality.Lipids in health and disease · 2023Article
- Triglyceride-Glucose Index and Cardiovascular Events in Kidney Transplant Recipients.Kidney international reports · 2023Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe combined association of triglyceride-glucose (TyG) index and different systolic blood pressure (SBP) levels with all-cause and cardiovascular mortality among the general population remains unclear.
methodsIn this study, 6245 individuals were from the National Health and Nutrition Examination Survey (1999-2002). The study endpoints were all-cause and cardiovascular mortality. Multivariate Cox proportional hazards regression models were used to explore the combined association of TyG index and different SBP levels with all-cause and cardiovascular mortality.
resultsDuring a mean follow-up period of 66.8 months, a total of 284 all-cause deaths (331/100000 person-years) and 61 cardiovascular deaths (66/100000 person-years) were recorded. Multivariate Cox regression analysis revealed that the combination of low TyG index and low SBP (< 120 mmHg and < 130 mmHg) was associated with a reduced risk of all-cause and cardiovascular mortality than others. However, survival benefit was not observed in the combined group with the low TyG index and SBP < 140 mmHg. Furthermore, the mortality rate in the combined group of low TyG index and low SBP gradually increased with the elevation of SBP level.
conclusionThe combination of low TyG index and low SBP (< 120 mmHg and < 130 mmHg) was associated with a lower risk of all-cause and cardiovascular mortality. However, no survival benefit was observed in the combined group of low TyG index and SBP < 140 mmHg.
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