Evidence map›Paper›PMID 36266544›Full record

ArticleNature metabolism2022

Bacterial hydrogen sulfide drives cryptic redox chemistry in gut microbial communities.

Sarah J Wolfson, Reese Hitchings, Karina Peregrina, Ziv Cohen, Saad Khan, Tugba Yilmaz, Marcel Malena, Edgar D Goluch, Leonard Augenlicht, Libusha Kelly

Open access · greenAbstract read
In one paragraph

Article in Nature metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Biosynthesis of HAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  6. Review
  7. Pharmacomicrobiomics.Clinical pharmacology and therapeutics · 2025
    Review
  8. Article
  9. Diet's impact on gut microbial assemblage in health and disease.The Journal of clinical investigation · 2025
    Review
  10. Microbial metabolism of host-derived antioxidants.Current opinion in chemical biology · 2025
    Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Sarah J Wolfson *Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, NY, USA.ORCID http://orcid.org/0000-0001-9774-0977
Reese Hitchings *Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, NY, USA.
Karina PeregrinaDepartments of Medicine and Cell Biology, Albert Einstein College of Medicine, Bronx, NY, USA.
Ziv CohenDepartment of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, NY, USA.
Saad KhanDepartment of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, NY, USA.
Tugba YilmazDepartment of Chemical Engineering, Northeastern University, Boston, MA, USA.
Marcel MalenaDepartment of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, NY, USA.
Edgar D GoluchDepartment of Chemical Engineering, Northeastern University, Boston, MA, USA.
Leonard AugenlichtDepartments of Medicine and Cell Biology, Albert Einstein College of Medicine, Bronx, NY, USA.
Libusha KellyDepartment of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, NY, USA. libusha.kelly@einsteinmed.edu.ORCID http://orcid.org/0000-0002-7303-1022
Albert Einstein College of Medicine · USNortheastern University · US

Funding

WORD PROCESSORP30CA013330 · NCI · YESHIVA UNIVERSITY · PI THOMAS E ROHAN · 1985 to 2026
$111.2M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007288 · NIGMS · YESHIVA UNIVERSITY · PI AKABAS, MYLES H. · 1985 to 2022
$35.6M
In Vivo Sickle Cell Vasoocclusion: Adhesion MechanismsR01HL069438 · NHLBI · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI KELLY, LIBUSHA · 2001 to 2024
$9.5M
Geographic Medicine and Emerging InfectionsT32AI070117 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI WEISS, LOUIS M. · 2008 to 2023
$5.1M
Nutritionally Driven Sporadic Intestinal Tumors: Impact on Stem CellsR01CA229216 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI AUGENLICHT, LEONARD H · 2018 to 2022
$2.4M
A Major Nutritional Effect on Intestinal Stem Cells and TumorsR01CA214625 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI AUGENLICHT, LEONARD H · 2018 to 2022
$1.6M
Clinical and Translational Science AwardTL1TR001072 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI SHAMOON, HARRY · 2013 to 2017
$909k
NCATS NIH HHS TL1 TR001072NCI NIH HHS P30 CA013330NCI NIH HHS R01 CA214625NCI NIH HHS R01 CA229216NHLBI NIH HHS R01 HL069438NIAID NIH HHS T32 AI070117NIGMS NIH HHS T32 GM007288
6 · The paper itself

Abstract

Microbial biochemistry contributes to a dynamic environment in the gut. Yet, how bacterial metabolites such as hydrogen sulfide (H

Indexed as

Hydrogen SulfideMicrobiotaAnimalsAzo CompoundsBacteriaColoring AgentsEscherichia coliHumansMaleMiceOxidation-ReductionSulfidesSulfurXenobioticsAzo CompoundsColoring AgentsHydrogen SulfideSulfidesSulfurXenobiotics

Identifiers

PMID36266544
PMCPMC11328334
OpenAlexW4306888845

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.