Evidence map›Paper›PMID 36266447›Full record

ReviewExperimental & molecular medicine2022

8-Oxoguanine: from oxidative damage to epigenetic and epitranscriptional modification.

Ja Young Hahm, Jongyeun Park, Eun-Sook Jang, Sung Wook Chi

Open access · goldAbstract readReview
In one paragraph

Review in Experimental & molecular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 172 papers.

0numbers the graph read from it
0cells of the map it votes in
172citing papers in PubMed
20.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

172 citing papers in PubMed, 263 citations in OpenAlex.

  1. Article
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  8. Review
  9. Article
  10. An Integrated DNA Nanoprobe for Intranuclear Imaging and In Situ Profiling of OGG1 Activity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  11. Article
  12. Article
  13. Endocrine Disruptors and Gynecological Malignancies.Diagnostics (Basel, Switzerland) · 2026
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

112 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ja Young Hahm *Department of Life Sciences, Korea University, Seoul, 02481, Republic of Korea.ORCID http://orcid.org/0000-0001-9989-9113
Jongyeun Park *Department of Life Sciences, Korea University, Seoul, 02481, Republic of Korea.ORCID http://orcid.org/0000-0001-7394-5361
Eun-Sook JangDepartment of Life Sciences, Korea University, Seoul, 02481, Republic of Korea.
Sung Wook ChiDepartment of Life Sciences, Korea University, Seoul, 02481, Republic of Korea. chi13@korea.ac.kr.ORCID http://orcid.org/0000-0002-8035-8242
Korea University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In pathophysiology, reactive oxygen species control diverse cellular phenotypes by oxidizing biomolecules. Among these, the guanine base in nucleic acids is the most vulnerable to producing 8-oxoguanine, which can pair with adenine. Because of this feature, 8-oxoguanine in DNA (8-oxo-dG) induces a G > T (C > A) mutation in cancers, which can be deleterious and thus actively repaired by DNA repair pathways. 8-Oxoguanine in RNA (o

Indexed as

DNA RepairGuanine8-Hydroxy-2'-DeoxyguanosineDNA DamageEpigenesis, GeneticOxidative StressRNA8-Hydroxy-2'-Deoxyguanosine8-hydroxyguanineGuanineRNA

Identifiers

PMID36266447
PMCPMC9636213
OpenAlexW4306939094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.