Evidence map›Paper›PMID 36266403›Full record

ArticleScientific reports2022

Prediction of malignant lymph nodes in NSCLC by machine-learning classifiers using EBUS-TBNA and PET/CT.

Maja Guberina, Ken Herrmann, Christoph Pöttgen, Nika Guberina, Hubertus Hautzel, Thomas Gauler, Till Ploenes, Lale Umutlu, Axel Wetter, Dirk Theegarten and 9 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
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  7. Review
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  10. Advances in lymphatic metastasis of non-small cell lung cancer.Cell communication and signaling : CCS · 2024
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  14. Lung Cancer Staging: Imaging and Potential Pitfalls.Diagnostics (Basel, Switzerland) · 2023
    Review
  15. Article
  16. The different manifestations ofFrontiers in nuclear medicine · 2022
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Maja GuberinaDepartment of Radiotherapy, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Hufelandstr. 55, 45147, Essen, Germany. maja.guberina@uk-essen.de.
Ken HerrmannGerman Cancer Consortium (DKTK), Partner Site University Hospital Essen, Essen, Germany.
Christoph PöttgenDepartment of Radiotherapy, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Hufelandstr. 55, 45147, Essen, Germany.
Nika GuberinaDepartment of Radiotherapy, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Hufelandstr. 55, 45147, Essen, Germany.
Hubertus HautzelGerman Cancer Consortium (DKTK), Partner Site University Hospital Essen, Essen, Germany.
Thomas GaulerDepartment of Radiotherapy, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Hufelandstr. 55, 45147, Essen, Germany.
Till PloenesDepartment of Thoracic Surgery and Thoracic Endoscopy, West German Cancer Center, University Medicine Essen - Ruhrlandklinik, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Lale UmutluInstitute of Diagnostic, Interventional Radiology and Neuroradiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Axel WetterInstitute of Diagnostic, Interventional Radiology and Neuroradiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Dirk TheegartenInstitute of Pathology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Clemens AignerDepartment of Thoracic Surgery and Thoracic Endoscopy, West German Cancer Center, University Medicine Essen - Ruhrlandklinik, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Wilfried E E EberhardtDepartment of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Martin MetzenmacherDepartment of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Marcel WieswegDepartment of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Martin SchulerGerman Cancer Consortium (DKTK), Partner Site University Hospital Essen, Essen, Germany.
Rüdiger Karpf-WisselDepartment of Pulmonary Medicine, Section of Interventional Pneumology, West German Cancer Center, University Medicine Essen - Ruhrlandklinik, University Duisburg-Essen, Essen, Germany.
Alina Santiago GarciaDepartment of Radiotherapy, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Hufelandstr. 55, 45147, Essen, Germany.
Kaid DarwicheDepartment of Pulmonary Medicine, Section of Interventional Pneumology, West German Cancer Center, University Medicine Essen - Ruhrlandklinik, University Duisburg-Essen, Essen, Germany.
Martin StuschkeDepartment of Radiotherapy, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Hufelandstr. 55, 45147, Essen, Germany.
Ruhrlandklinik · DEDeutschen Konsortium für Translationale Krebsforschung · DEEssen University Hospital · DEUniversity of Duisburg-Essen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate determination of lymph-node (LN) metastases is a prerequisite for high precision radiotherapy. The primary aim is to characterise the performance of PET/CT-based machine-learning classifiers to predict LN-involvement by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in stage-III NSCLC. Prediction models for LN-positivity based on [

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsFluorodeoxyglucose F18HumansLymphatic MetastasisLymph NodesMachine LearningNeoplasm StagingPositron Emission Tomography Computed TomographyRetrospective StudiesFluorodeoxyglucose F18

Identifiers

PMID36266403
PMCPMC9584941
OpenAlexW4306871366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.