ArticleNature microbiology2022
Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome.
Article in Nature microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Bacillus drives functional states in synthetic plant root bacterial communities.Genome biology · 2025Pooled it
- AUXIN RESPONSE FACTORs: from transcription factors to auxin effectors.The New phytologist · 2026Review
- Unlocking the power ofmSystems · 2026Article
- TagR, a newly identified member of the MarR family of transcriptional regulators, represses the NRPS operon inMicrobiology spectrum · 2026Article
- A DNA damage-activated kinase phosphorylates a transcriptional repressor to control bacterial immune pathway expression.The EMBO journal · 2026Article
- Auxin biosynthesis and signaling drive virulence and plant adaptation in Dickeya dadantii.PLoS pathogens · 2026Article
- The phytohormone indole-3-acetic acid induces quorum sensing signal DSF turnover via a positive feedback biosynthetic loop in the phytopathogen Xanthomonas campestris.Stress biology · 2026Article
- The plant microbiota: From theoretical advances to applications.Fundamental research · 2026Review
- Ribosomal RNA operon copy number: A trait-informed framework to close the microbial cultivation gap.iMetaOmics · 2026Article
- A DNA damage-activated kinase controls bacterial immune pathway expression.bioRxiv : the preprint server for biology · 2026Article
- Large-scale multi-omics unveils host-microbiome interactions driving root development and nitrogen acquisition.Nature plants · 2026Article
- Response and degradation of indole-3-aceticacid by the plant growth-promoting rhizobacteria Variovorax boronicumulans.Applied microbiology and biotechnology · 2026Article
- Article
- Mechanisms of Microorganisms Alleviating Drought and Salt Stresses in Plants.Microorganisms · 2025Review
- Engineering auxin degradation into root-associated bacteria promotes plant growth.bioRxiv : the preprint server for biology · 2025Article
- Microbial drivers of root plasticity.The New phytologist · 2025Review
- Microbiomes in action: multifaceted benefits and challenges across academic disciplines.Frontiers in microbiology · 2025Review
- Systematic characterization of plant-associated bacteria that can degrade indole-3-acetic acid.PLoS biology · 2024Article
- PGPR: Key to Enhancing Crop Productivity and Achieving Sustainable Agriculture.Current microbiology · 2024Review
- Auxin-mediated regulation of susceptibility to toxic metabolites, c-di-GMP levels, and phage infection in the rhizobacteriummSystems · 2024Article
Corrections and comments
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Authors and funding
14 authors at 2 institutions in 2 countries.
Funding
Abstract
Chemical signalling in the plant microbiome can have drastic effects on microbial community structure, and on host growth and development. Previously, we demonstrated that the auxin metabolic signal interference performed by the bacterial genus Variovorax via an auxin degradation locus was essential for maintaining stereotypic root development in an ecologically relevant bacterial synthetic community. Here, we dissect the Variovorax auxin degradation locus to define the genes iadDE as necessary and sufficient for indole-3-acetic acid (IAA) degradation and signal interference. We determine the crystal structures and binding properties of the operon's MarR-family repressor with IAA and other auxins. Auxin degradation operons were identified across the bacterial tree of life and we define two distinct types on the basis of gene content and metabolic products: iac-like and iad-like. The structures of MarRs from representatives of each auxin degradation operon type establish that each has distinct IAA-binding pockets. Comparison of representative IAA-degrading strains from diverse bacterial genera colonizing Arabidopsis plants show that while all degrade IAA, only strains containing iad-like auxin-degrading operons interfere with auxin signalling in a complex synthetic community context. This suggests that iad-like operon-containing bacterial strains, including Variovorax species, play a key ecological role in modulating auxins in the plant microbiome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.