Evidence map›Paper›PMID 36266314›Full record

ArticleNature communications2022

Central role of Prominin-1 in lipid rafts during liver regeneration.

Myeong-Suk Bahn, Dong-Min Yu, Myoungwoo Lee, Sung-Je Jo, Ji-Won Lee, Ho-Chul Kim, Hyun Lee, Hong Lim Kim, Arum Kim, Jeong-Ho Hong and 4 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Myeong-Suk Bahn *Division of Life Sciences, Korea University, Seoul, 02841, Korea.
Dong-Min Yu *Division of Life Sciences, Korea University, Seoul, 02841, Korea.
Myoungwoo LeeDivision of Life Sciences, Korea University, Seoul, 02841, Korea.ORCID 0000-0002-7516-0493
Sung-Je JoDivision of Life Sciences, Korea University, Seoul, 02841, Korea.
Ji-Won LeeDivision of Life Sciences, Korea University, Seoul, 02841, Korea.
Ho-Chul KimDivision of Life Sciences, Korea University, Seoul, 02841, Korea.
Hyun LeeDivision of Life Sciences, Korea University, Seoul, 02841, Korea.
Hong Lim KimLaboratory of Electron Microscope, Integrative Research Support Center, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Arum KimDivision of Life Sciences, Korea University, Seoul, 02841, Korea.
Jeong-Ho HongDivision of Life Sciences, Korea University, Seoul, 02841, Korea.ORCID 0000-0003-1902-1605
Jun Seok KimDivision of Life Sciences, Korea University, Seoul, 02841, Korea.
Seung-Hoi KooDivision of Life Sciences, Korea University, Seoul, 02841, Korea.ORCID 0000-0001-8769-2879
Jae-Seon LeeResearch Center for Controlling Intercellular Communication, College of Medicine, Inha University, Incheon, 22212, Korea.ORCID 0000-0001-6002-5267
Young-Gyu KoDivision of Life Sciences, Korea University, Seoul, 02841, Korea. ygko@korea.ac.kr.ORCID 0000-0002-0969-2598
Korea University · KRInha University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prominin-1, a lipid raft protein, is required for maintaining cancer stem cell properties in hepatocarcinoma cell lines, but its physiological roles in the liver have not been well studied. Here, we investigate the role of Prominin-1 in lipid rafts during liver regeneration and show that expression of Prominin-1 increases after 2/3 partial hepatectomy or CCl

Indexed as

Interleukin-6Liver RegenerationAC133 AntigenAnimalsCytokine Receptor gp130Membrane MicrodomainsMiceMice, KnockoutAC133 AntigenCytokine Receptor gp130Interleukin-6

Identifiers

PMID36266314
PMCPMC9585078
OpenAlexW4306878800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.