Evidence map›Paper›PMID 36266283›Full record

ArticleNature communications2022

Force-triggered rapid microstructure growth on hydrogel surface for on-demand functions.

Qifeng Mu, Kunpeng Cui, Zhi Jian Wang, Takahiro Matsuda, Wei Cui, Hinako Kato, Shotaro Namiki, Tomoko Yamazaki, Martin Frauenlob, Takayuki Nonoyama and 4 more

Abstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. 3D printable tough hydrogel actuators.Materials horizons · 2026
    Review
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  13. Mechanochemistry: Fundamental Principles and Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Qifeng MuGraduate School of Life Science, Hokkaido University, N21W11, Kita-ku, Sapporo, 001-0021, Japan.
Kunpeng CuiInstitute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University, N21W10, Kita-ku, Sapporo, 001-0021, Japan.
Zhi Jian WangGraduate School of Life Science, Hokkaido University, N21W11, Kita-ku, Sapporo, 001-0021, Japan.ORCID 0000-0001-8577-3798
Takahiro MatsudaFaculty of Advanced Life Science, Hokkaido University, N21W11, Kita-ku, Sapporo, 001-0021, Japan.ORCID 0000-0001-9681-8007
Wei CuiFaculty of Advanced Life Science, Hokkaido University, N21W11, Kita-ku, Sapporo, 001-0021, Japan.ORCID 0000-0003-3449-8524
Hinako KatoGraduate School of Life Science, Hokkaido University, N21W11, Kita-ku, Sapporo, 001-0021, Japan.
Shotaro NamikiGraduate School of Life Science, Hokkaido University, N21W11, Kita-ku, Sapporo, 001-0021, Japan.
Tomoko YamazakiGraduate School of Life Science, Hokkaido University, N21W11, Kita-ku, Sapporo, 001-0021, Japan.
Martin FrauenlobGraduate School of Life Science, Hokkaido University, N21W11, Kita-ku, Sapporo, 001-0021, Japan.ORCID 0000-0001-7460-9378
Takayuki NonoyamaFaculty of Advanced Life Science, Hokkaido University, N21W11, Kita-ku, Sapporo, 001-0021, Japan.ORCID 0000-0001-8554-0636
Masumi TsudaInstitute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University, N21W10, Kita-ku, Sapporo, 001-0021, Japan.ORCID 0000-0001-5400-5905
Shinya TanakaInstitute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University, N21W10, Kita-ku, Sapporo, 001-0021, Japan.ORCID 0000-0001-6470-3301
Tasuku NakajimaInstitute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University, N21W10, Kita-ku, Sapporo, 001-0021, Japan. tasuku@sci.hokudai.ac.jp.ORCID 0000-0002-2235-3478
Jian Ping GongInstitute for Chemical Reaction Design and Discovery (WPI-ICReDD), Hokkaido University, N21W10, Kita-ku, Sapporo, 001-0021, Japan. gong@sci.hokudai.ac.jp.ORCID 0000-0003-2228-2750

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Living organisms share the ability to grow various microstructures on their surface to achieve functions. Here we present a force stamp method to grow microstructures on the surface of hydrogels based on a force-triggered polymerisation mechanism of double-network hydrogels. This method allows fast spatial modulation of the morphology and chemistry of the hydrogel surface within seconds for on-demand functions. We demonstrate the oriented growth of cells and directional transportation of water droplets on the engineered hydrogel surfaces. This force-triggered method to chemically engineer the hydrogel surfaces provides a new tool in addition to the conventional methods using light or heat, and will promote the wide application of hydrogels in various fields.

Indexed as

HydrogelsWaterHydrogelsWater

Identifiers

PMID36266283
PMCPMC9585076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.