Evidence map›Paper›PMID 36266164›Full record

ReviewTrends in endocrinology and metabolism: TEM2022

Cortisol and cardiometabolic disease: a target for advancing health equity.

Robin Ortiz, Bjorn Kluwe, Sophie Lazarus, Mary N Teruel, Joshua J Joseph

Open access · greenAbstract readReview
In one paragraph

Review in Trends in endocrinology and metabolism: TEM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
6.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
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  4. Trial
  5. Distinct functional roles ofAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2026
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  10. Inflammaging and Cardiovascular Risk in Old Women.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Robin OrtizDepartment of Pediatrics, NYU Grossman School of Medicine, New York, NY, USA; Department of Population Health, NYU Grossman School of Medicine, New York, NY, USA; Institute for Excellence of Health Equity, NYU Langone Health, New York, NY, USA.
Bjorn KluweDivision of Endocrinology, Diabetes and Metabolism, The Ohio State University College of Medicine, Columbus, OH, USA.
Sophie LazarusDepartment of Psychology, The Ohio State University, Columbus, OH, USA.
Mary N TeruelDepartment of Biochemistry and the Drukier Institute for Children's Health, Weill Cornell Medicine, New York, NY, USA.
Joshua J JosephDivision of Endocrinology, Diabetes and Metabolism, The Ohio State University College of Medicine, Columbus, OH, USA. Electronic address: Joshua.Joseph@osumc.edu.
The Ohio State University · USCornell University · USNew York University · US

Funding

Linking education, produce provision, and community referrals to improve diabetes care (LINK)R01DK132403 · NIDDK · OHIO STATE UNIVERSITY · PI Joshua J Joseph, Daniel M Walker · 2022 to 2026
$3.3M
Cell cycle control of adipogenesisR01DK131432 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI Mary N Teruel · 2023 to 2026
$2.0M
The Role of The Renin-Angiotensin-Aldosterone System, ARMC5, and Neprilysin in Glucose Metabolism among African AmericansK23DK117041 · NIDDK · OHIO STATE UNIVERSITY · PI JOSEPH, JOSHUA J · 2018 to 2022
$1.0M
Cell cycle control of adipogenesisR56DK131432 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI TERUEL, MARY N · 2021 to 2021
$211k
NIDDK NIH HHS K23 DK117041NIDDK NIH HHS R01 DK131432NIDDK NIH HHS R01 DK132403NIDDK NIH HHS R56 DK131432
6 · The paper itself

Abstract

Stress, in both intrinsic psychosocial and extrinsic physical environmental forms, can impact the development of, and outcomes in, cardiovascular disease (CVD) through allostatic load. Cortisol is a core hormonal mediator of allostatic load produced in response to various stresses. Alterations in morning serum cortisol and daily diurnal cortisol have been associated with adiposity, dyslipidemia, incident diabetes, and CVDs such as hypertension. The review examines the role of cortisol as a key mechanistic link between stress physiology and cardiometabolic disease. Importantly, we discuss the role of targeting cortisol through pharmacological, behavioral, and environmental interventions to advance health equity in cardiometabolic disease.

Indexed as

Cardiovascular DiseasesHealth EquityHypertensionHumansHydrocortisoneStress, PsychologicalHydrocortisoneadiposityadrenalcardiometabolic diseasecortisoldiabeteshealth equitystress

Identifiers

PMID36266164
PMCPMC9676046
OpenAlexW4306649432

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.