ArticleNeurology2022
Discordance and Concordance Between Cerebrospinal and [
Open access · greenAbstract read
In one paragraph
Article in Neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- The Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD-ADRD): Executive summary of recommendations for specialty care.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Guideline
- Real-world comparison of brain [EClinicalMedicine · 2026Article
- The Diagnostic Role of FDG-PET in Dementias Presenting with Language and Behavioral Symptom.Turk psikiyatri dergisi = Turkish journal of psychiatry · 2026Article
- Comparison of Plasma p-tau217 and [Neurology · 2025Article
- Usefulness of Cerebrospinal Fluid Alzheimer's disease biomarkers in older patients: Evidence from a national multicenter prospective study.The journal of prevention of Alzheimer's disease · 2025Article
- Plasma phosphorylated tau181 outperforms [European journal of neurology · 2024Article
- P2X7 Receptor: an Emerging Target in Alzheimer's Disease.Molecular neurobiology · 2024Review
- Skin-brain axis in Alzheimer's disease - Pathologic, diagnostic, and therapeutic implications: A Hypothetical Review.Aging and disease · 2024Review
- Comparison of immunoassay- with mass spectrometry-derived p-tau quantification for the detection of Alzheimer's disease pathology.Molecular neurodegeneration · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 1 institution in 2 countries.
Kely Mónica QuispialayaFrom the Translational Neuroimaging Laboratory (K.M.Q., J.T., M.Z., J.F.-A., F.L., S.G., P.V., P.R.-N.), The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, Montreal, Quebec, Canada; Research Institute of the McGill University Health Centre (K.M.Q., A.A., B.J.-C., B.G.), Montreal, Quebec, Canada; Departments of Medicine (K.M.Q., B.J.-C., B.G.) and Neurology and Neurosurgery (J.T., M.Z., J.F.-A., F.L., J.-P.S., S.G., P.V., P.R.-N.), McGill University, Montreal, Quebec, Canada; Montreal Neurological Institute (J.T., M.Z., J.F.-A., F.L., G.M., J.-P.S., P.R.-N.), Montreal, Quebec, Canada; Department of Radiochemistry (G.M.), McGill University, Montreal, Quebec, Canada; Department of Psychiatry (T.P.), Pittsburgh University, PA; and Department of Psychiatry (S.G., P.R.-N.), McGill University, Montreal, Quebec, Canada.
Joseph TherriaultFrom the Translational Neuroimaging Laboratory (K.M.Q., J.T., M.Z., J.F.-A., F.L., S.G., P.V., P.R.-N.), The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, Montreal, Quebec, Canada; Research Institute of the McGill University Health Centre (K.M.Q., A.A., B.J.-C., B.G.), Montreal, Quebec, Canada; Departments of Medicine (K.M.Q., B.J.-C., B.G.) and Neurology and Neurosurgery (J.T., M.Z., J.F.-A., F.L., J.-P.S., S.G., P.V., P.R.-N.), McGill University, Montreal, Quebec, Canada; Montreal Neurological Institute (J.T., M.Z., J.F.-A., F.L., G.M., J.-P.S., P.R.-N.), Montreal, Quebec, Canada; Department of Radiochemistry (G.M.), McGill University, Montreal, Quebec, Canada; Department of Psychiatry (T.P.), Pittsburgh University, PA; and Department of Psychiatry (S.G., P.R.-N.), McGill University, Montreal, Quebec, Canada.
Antonio AliagaFrom the Translational Neuroimaging Laboratory (K.M.Q., J.T., M.Z., J.F.-A., F.L., S.G., P.V., P.R.-N.), The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, Montreal, Quebec, Canada; Research Institute of the McGill University Health Centre (K.M.Q., A.A., B.J.-C., B.G.), Montreal, Quebec, Canada; Departments of Medicine (K.M.Q., B.J.-C., B.G.) and Neurology and Neurosurgery (J.T., M.Z., J.F.-A., F.L., J.-P.S., S.G., P.V., P.R.-N.), McGill University, Montreal, Quebec, Canada; Montreal Neurological Institute (J.T., M.Z., J.F.-A., F.L., G.M., J.-P.S., P.R.-N.), Montreal, Quebec, Canada; Department of Radiochemistry (G.M.), McGill University, Montreal, Quebec, Canada; Department of Psychiatry (T.P.), Pittsburgh University, PA; and Department of Psychiatry (S.G., P.R.-N.), McGill University, Montreal, Quebec, Canada.
Maria ZimmermannFrom the Translational Neuroimaging Laboratory (K.M.Q., J.T., M.Z., J.F.-A., F.L., S.G., P.V., P.R.-N.), The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, Montreal, Quebec, Canada; Research Institute of the McGill University Health Centre (K.M.Q., A.A., B.J.-C., B.G.), Montreal, Quebec, Canada; Departments of Medicine (K.M.Q., B.J.-C., B.G.) and Neurology and Neurosurgery (J.T., M.Z., J.F.-A., F.L., J.-P.S., S.G., P.V., P.R.-N.), McGill University, Montreal, Quebec, Canada; Montreal Neurological Institute (J.T., M.Z., J.F.-A., F.L., G.M., J.-P.S., P.R.-N.), Montreal, Quebec, Canada; Department of Radiochemistry (G.M.), McGill University, Montreal, Quebec, Canada; Department of Psychiatry (T.P.), Pittsburgh University, PA; and Department of Psychiatry (S.G., P.R.-N.), McGill University, Montreal, Quebec, Canada.
Jaime Fernandez-AriasFrom the Translational Neuroimaging Laboratory (K.M.Q., J.T., M.Z., J.F.-A., F.L., S.G., P.V., P.R.-N.), The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, Montreal, Quebec, Canada; Research Institute of the McGill University Health Centre (K.M.Q., A.A., B.J.-C., B.G.), Montreal, Quebec, Canada; Departments of Medicine (K.M.Q., B.J.-C., B.G.) and Neurology and Neurosurgery (J.T., M.Z., J.F.-A., F.L., J.-P.S., S.G., P.V., P.R.-N.), McGill University, Montreal, Quebec, Canada; Montreal Neurological Institute (J.T., M.Z., J.F.-A., F.L., G.M., J.-P.S., P.R.-N.), Montreal, Quebec, Canada; Department of Radiochemistry (G.M.), McGill University, Montreal, Quebec, Canada; Department of Psychiatry (T.P.), Pittsburgh University, PA; and Department of Psychiatry (S.G., P.R.-N.), McGill University, Montreal, Quebec, Canada.
Firoza LussierFrom the Translational Neuroimaging Laboratory (K.M.Q., J.T., M.Z., J.F.-A., F.L., S.G., P.V., P.R.-N.), The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, Montreal, Quebec, Canada; Research Institute of the McGill University Health Centre (K.M.Q., A.A., B.J.-C., B.G.), Montreal, Quebec, Canada; Departments of Medicine (K.M.Q., B.J.-C., B.G.) and Neurology and Neurosurgery (J.T., M.Z., J.F.-A., F.L., J.-P.S., S.G., P.V., P.R.-N.), McGill University, Montreal, Quebec, Canada; Montreal Neurological Institute (J.T., M.Z., J.F.-A., F.L., G.M., J.-P.S., P.R.-N.), Montreal, Quebec, Canada; Department of Radiochemistry (G.M.), McGill University, Montreal, Quebec, Canada; Department of Psychiatry (T.P.), Pittsburgh University, PA; and Department of Psychiatry (S.G., P.R.-N.), McGill University, Montreal, Quebec, Canada.
Gassan MassarwehFrom the Translational Neuroimaging Laboratory (K.M.Q., J.T., M.Z., J.F.-A., F.L., S.G., P.V., P.R.-N.), The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, Montreal, Quebec, Canada; Research Institute of the McGill University Health Centre (K.M.Q., A.A., B.J.-C., B.G.), Montreal, Quebec, Canada; Departments of Medicine (K.M.Q., B.J.-C., B.G.) and Neurology and Neurosurgery (J.T., M.Z., J.F.-A., F.L., J.-P.S., S.G., P.V., P.R.-N.), McGill University, Montreal, Quebec, Canada; Montreal Neurological Institute (J.T., M.Z., J.F.-A., F.L., G.M., J.-P.S., P.R.-N.), Montreal, Quebec, Canada; Department of Radiochemistry (G.M.), McGill University, Montreal, Quebec, Canada; Department of Psychiatry (T.P.), Pittsburgh University, PA; and Department of Psychiatry (S.G., P.R.-N.), McGill University, Montreal, Quebec, Canada.
Tharick PascoalFrom the Translational Neuroimaging Laboratory (K.M.Q., J.T., M.Z., J.F.-A., F.L., S.G., P.V., P.R.-N.), The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, Montreal, Quebec, Canada; Research Institute of the McGill University Health Centre (K.M.Q., A.A., B.J.-C., B.G.), Montreal, Quebec, Canada; Departments of Medicine (K.M.Q., B.J.-C., B.G.) and Neurology and Neurosurgery (J.T., M.Z., J.F.-A., F.L., J.-P.S., S.G., P.V., P.R.-N.), McGill University, Montreal, Quebec, Canada; Montreal Neurological Institute (J.T., M.Z., J.F.-A., F.L., G.M., J.-P.S., P.R.-N.), Montreal, Quebec, Canada; Department of Radiochemistry (G.M.), McGill University, Montreal, Quebec, Canada; Department of Psychiatry (T.P.), Pittsburgh University, PA; and Department of Psychiatry (S.G., P.R.-N.), McGill University, Montreal, Quebec, Canada.
Jean-Paul SoucyFrom the Translational Neuroimaging Laboratory (K.M.Q., J.T., M.Z., J.F.-A., F.L., S.G., P.V., P.R.-N.), The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, Montreal, Quebec, Canada; Research Institute of the McGill University Health Centre (K.M.Q., A.A., B.J.-C., B.G.), Montreal, Quebec, Canada; Departments of Medicine (K.M.Q., B.J.-C., B.G.) and Neurology and Neurosurgery (J.T., M.Z., J.F.-A., F.L., J.-P.S., S.G., P.V., P.R.-N.), McGill University, Montreal, Quebec, Canada; Montreal Neurological Institute (J.T., M.Z., J.F.-A., F.L., G.M., J.-P.S., P.R.-N.), Montreal, Quebec, Canada; Department of Radiochemistry (G.M.), McGill University, Montreal, Quebec, Canada; Department of Psychiatry (T.P.), Pittsburgh University, PA; and Department of Psychiatry (S.G., P.R.-N.), McGill University, Montreal, Quebec, Canada.
Serge GauthierFrom the Translational Neuroimaging Laboratory (K.M.Q., J.T., M.Z., J.F.-A., F.L., S.G., P.V., P.R.-N.), The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, Montreal, Quebec, Canada; Research Institute of the McGill University Health Centre (K.M.Q., A.A., B.J.-C., B.G.), Montreal, Quebec, Canada; Departments of Medicine (K.M.Q., B.J.-C., B.G.) and Neurology and Neurosurgery (J.T., M.Z., J.F.-A., F.L., J.-P.S., S.G., P.V., P.R.-N.), McGill University, Montreal, Quebec, Canada; Montreal Neurological Institute (J.T., M.Z., J.F.-A., F.L., G.M., J.-P.S., P.R.-N.), Montreal, Quebec, Canada; Department of Radiochemistry (G.M.), McGill University, Montreal, Quebec, Canada; Department of Psychiatry (T.P.), Pittsburgh University, PA; and Department of Psychiatry (S.G., P.R.-N.), McGill University, Montreal, Quebec, Canada.
Bertrand Jean-ClaudeFrom the Translational Neuroimaging Laboratory (K.M.Q., J.T., M.Z., J.F.-A., F.L., S.G., P.V., P.R.-N.), The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, Montreal, Quebec, Canada; Research Institute of the McGill University Health Centre (K.M.Q., A.A., B.J.-C., B.G.), Montreal, Quebec, Canada; Departments of Medicine (K.M.Q., B.J.-C., B.G.) and Neurology and Neurosurgery (J.T., M.Z., J.F.-A., F.L., J.-P.S., S.G., P.V., P.R.-N.), McGill University, Montreal, Quebec, Canada; Montreal Neurological Institute (J.T., M.Z., J.F.-A., F.L., G.M., J.-P.S., P.R.-N.), Montreal, Quebec, Canada; Department of Radiochemistry (G.M.), McGill University, Montreal, Quebec, Canada; Department of Psychiatry (T.P.), Pittsburgh University, PA; and Department of Psychiatry (S.G., P.R.-N.), McGill University, Montreal, Quebec, Canada.
Brian GilfixFrom the Translational Neuroimaging Laboratory (K.M.Q., J.T., M.Z., J.F.-A., F.L., S.G., P.V., P.R.-N.), The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, Montreal, Quebec, Canada; Research Institute of the McGill University Health Centre (K.M.Q., A.A., B.J.-C., B.G.), Montreal, Quebec, Canada; Departments of Medicine (K.M.Q., B.J.-C., B.G.) and Neurology and Neurosurgery (J.T., M.Z., J.F.-A., F.L., J.-P.S., S.G., P.V., P.R.-N.), McGill University, Montreal, Quebec, Canada; Montreal Neurological Institute (J.T., M.Z., J.F.-A., F.L., G.M., J.-P.S., P.R.-N.), Montreal, Quebec, Canada; Department of Radiochemistry (G.M.), McGill University, Montreal, Quebec, Canada; Department of Psychiatry (T.P.), Pittsburgh University, PA; and Department of Psychiatry (S.G., P.R.-N.), McGill University, Montreal, Quebec, Canada.
Paolo VitaliFrom the Translational Neuroimaging Laboratory (K.M.Q., J.T., M.Z., J.F.-A., F.L., S.G., P.V., P.R.-N.), The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, Montreal, Quebec, Canada; Research Institute of the McGill University Health Centre (K.M.Q., A.A., B.J.-C., B.G.), Montreal, Quebec, Canada; Departments of Medicine (K.M.Q., B.J.-C., B.G.) and Neurology and Neurosurgery (J.T., M.Z., J.F.-A., F.L., J.-P.S., S.G., P.V., P.R.-N.), McGill University, Montreal, Quebec, Canada; Montreal Neurological Institute (J.T., M.Z., J.F.-A., F.L., G.M., J.-P.S., P.R.-N.), Montreal, Quebec, Canada; Department of Radiochemistry (G.M.), McGill University, Montreal, Quebec, Canada; Department of Psychiatry (T.P.), Pittsburgh University, PA; and Department of Psychiatry (S.G., P.R.-N.), McGill University, Montreal, Quebec, Canada.ORCID 0000-0001-8953-1542
Pedro Rosa-NetoFrom the Translational Neuroimaging Laboratory (K.M.Q., J.T., M.Z., J.F.-A., F.L., S.G., P.V., P.R.-N.), The McGill University Research Centre for Studies in Aging, Douglas Hospital, McGill University, Montreal, Quebec, Canada; Research Institute of the McGill University Health Centre (K.M.Q., A.A., B.J.-C., B.G.), Montreal, Quebec, Canada; Departments of Medicine (K.M.Q., B.J.-C., B.G.) and Neurology and Neurosurgery (J.T., M.Z., J.F.-A., F.L., J.-P.S., S.G., P.V., P.R.-N.), McGill University, Montreal, Quebec, Canada; Montreal Neurological Institute (J.T., M.Z., J.F.-A., F.L., G.M., J.-P.S., P.R.-N.), Montreal, Quebec, Canada; Department of Radiochemistry (G.M.), McGill University, Montreal, Quebec, Canada; Department of Psychiatry (T.P.), Pittsburgh University, PA; and Department of Psychiatry (S.G., P.R.-N.), McGill University, Montreal, Quebec, Canada. pedro.rosa@mcgill.ca.ORCID 0000-0001-9116-1376
Montreal Neurological Institute and Hospital · CA
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesTo assess the concordance and discordance between the core Alzheimer disease (AD) CSF biomarkers and [
methodsWe retrospectively assessed participants with atypical and/or early-onset dementia evaluated at a tertiary care memory clinic. All individuals underwent CSF evaluations for Aβ42, phosphorylated tau (P-tau181) and total tau, and brain [
resultsOne hundred thirty-six individuals had both [ DISCUSSION: CSF and [
Indexed as
Alzheimer DiseaseCognitive DysfunctionAmyloid beta-PeptidesBiomarkersFluorodeoxyglucose F18HumansPeptide FragmentsPositron-Emission TomographyRetrospective Studiestau ProteinsAmyloid beta-PeptidesBiomarkersFluorodeoxyglucose F18Peptide Fragmentstau Proteins
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.