Evidence map›Paper›PMID 36265940›Full record

ArticleJACC. Cardiovascular interventions2022

Temporal Trends, Practice Variation, and Associated Outcomes With IVUS Use During Peripheral Arterial Intervention.

Sanjay Divakaran, Sahil A Parikh, Beau M Hawkins, Siyan Chen, Yang Song, Subhash Banerjee, Kenneth Rosenfield, Eric A Secemsky

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in JACC. Cardiovascular interventions, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07353905 (Intravascular Ultrasound Imaging Guidance for Optimal Revascularization of Limb Arteries), which is not on this map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07353905 narecruitingnot on this mapstarted 2025, after this paper: background citation

Intravascular Ultrasound Imaging Guidance for Optimal Revascularization of Limb Arteries

TypeinterventionalSponsorBaylor Research InstituteRan2025 to 2028Enrolled350ConditionsPeripheral Arterial Disease, Lower Extremity Arterial DiseaseArmsIntravascular Ultrasound (IVUS), Angiographic-guided Intervention
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Trial
  5. Article
  6. Article
  7. Popliteal cystic adventitial disease unmasked by intravascular ultrasound.Journal of vascular surgery cases and innovative techniques · 2026
    Article
  8. Device design and applications of the novel JAVELIN peripheral intravascular lithotripsy catheter.Journal of vascular surgery cases and innovative techniques · 2026
    Article
  9. Intravascular Ultrasound in Chronic Limb-Threatening Ischemia Endovascular Revascularization: A Multidisciplinary Survey of Clinical Practices and Operator Perceptions.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  10. Review
  11. Article
  12. Article
  13. Intravascular Ultrasound Guidance During Peripheral Vascular Interventions: Long-term Clinical Outcomes and Costs From the Japanese Perspective.Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists · 2025
    Observational
  14. Article
  15. The Impact of Intravascular Ultrasound Use on 1-Year Outcomes After Infrapopliteal Endovascular Intervention.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Article
  16. Article
  17. Article
  18. Review
  19. Observational
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Sanjay DivakaranDivision of Cardiovascular Medicine and Cardiovascular Imaging Program, Brigham and Women's Hospital, Boston, Massachusetts, USA; Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA; Harvard Medical School, Boston, Massachusetts, USA. Electronic address: https://twitter.com/SanjayDivakaran.
Sahil A ParikhDivision of Cardiovascular Medicine, Columbia University Medical Center, New York, New York, USA.
Beau M HawkinsSection of Cardiovascular Diseases, University of Oklahoma, Oklahoma City, Oklahoma, USA.
Siyan ChenRichard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Yang SongRichard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Subhash BanerjeeDepartment of Internal Medicine, University of Texas Southwestern, Dallas, Texas, USA.
Kenneth RosenfieldDivision of Cardiology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Eric A SecemskyRichard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA; Harvard Medical School, Boston, Massachusetts, USA; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA. Electronic address: esecemsk@bidmc.harvard.edu.
Beth Israel Deaconess Medical Center · USColumbia University Irving Medical Center · USMassachusetts General Hospital · USThe University of Texas Southwestern Medical Center · USTwitter (United States) · USUniversity of Oklahoma · US

Funding

TUFTS--FIELDINGP30AG031679 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI SHALENDER BHASIN · 2008 to 2026
$23.9M
Shared Decision-Making to Improve the Health Status of Patients with Claudication: Developing and Implementing Strategies to Individualize Treatment DecisionsK23HL150290 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SECEMSKY, ERIC ALEXANDER · 2020 to 2024
$851k
NHLBI NIH HHS K23 HL150290NIA NIH HHS P30 AG031679
6 · The paper itself

Abstract

backgroundIntravascular ultrasound (IVUS) has been shown in limited prospective studies to improve procedural outcomes for patients undergoing lower extremity peripheral arterial intervention (PVI).

objectivesThe authors aimed to study temporal trends, practice variation, and associated outcomes with the use of IVUS during PVI among Medicare beneficiaries.

methodsAll PVIs performed from 2016 to 2019 among Medicare beneficiaries aged >65 years were included. Temporal trends in IVUS use were stratified by procedural location (inpatient, outpatient, or ambulatory surgery center [ASC]/office-based laboratory [OBL]) and physician specialty. The primary outcome was major adverse limb events (MALE). Inverse probability weighting was used to account for differences in baseline characteristics. Cox regression with competing risks was used to estimate weighted hazard ratios.

resultsDuring the study period, 543,488 PVIs were included, of which 63,372 (11.7%) used IVUS. A substantial growth in IVUS use was observed, which was driven by procedures performed in ASCs/OBLs (23.6% increase from quarter 1 of 2016 through quarter 4 of 2019). Among operators who used IVUS, there was also notable variation in use (median operator use 5.4% of cases; IQR: 2.2%-15.0%; range, <1%-100%). In weighted analysis, IVUS use during PVI was associated with a lower risk of MALE through a median of 514 days (adjusted hazard ratio: 0.73; 95% CI: 0.70-0.75; P < 0.0001).

conclusionsIn contemporary nationwide data, IVUS use during PVI has increased since 2016, driven by growth in the ASC/OBL setting. However, there remains substantial variation in operator practice. When used during PVI, IVUS was associated with a lower risk of short- and long-term MALE.

Indexed as

Endovascular ProceduresPeripheral Arterial DiseaseHumansMedicareProspective StudiesTreatment OutcomeUltrasonography, InterventionalUnited Statesintravascular ultrasoundmajor adverse limb event(s)peripheral arterial interventionperipheral artery disease

Identifiers

PMID36265940
PMCPMC9758975
OpenAlexW4306649299

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.