Evidence map›Paper›PMID 36265219›Full record

Trial reportGait & posture2022

An 8-week aerobic cycling intervention elicits improved gait velocity and biomechanics in persons with Parkinson's disease.

Susan M Linder, Elise Baron, Ken Learman, Mandy Miller Koop, Amanda Penko, Debbie Espy, Matt Streicher, Jay L Alberts

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Gait & posture, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Susan M LinderCleveland Clinic, Department of Physical Medicine and Rehabilitation, Cleveland, OH, USA; Cleveland Clinic, Department of Biomedical Engineering, Cleveland, OH, USA; Youngstown State University, Youngstown, OH, USA. Electronic address: linders@ccf.org.
Elise BaronCleveland Clinic, Department of Biomedical Engineering, Cleveland, OH, USA.
Ken LearmanYoungstown State University, Youngstown, OH, USA.
Mandy Miller KoopCleveland Clinic, Department of Biomedical Engineering, Cleveland, OH, USA.
Amanda PenkoCleveland Clinic, Department of Physical Medicine and Rehabilitation, Cleveland, OH, USA; Cleveland Clinic, Department of Biomedical Engineering, Cleveland, OH, USA.
Debbie EspyCleveland State University, Cleveland, OH, USA.
Matt StreicherCleveland Clinic, Concussion Center, Cleveland, OH, USA.
Jay L AlbertsCleveland Clinic, Department of Biomedical Engineering, Cleveland, OH, USA; Cleveland Clinic, Concussion Center, Cleveland, OH, USA; Cleveland Clinic, Center for Neurologic Restoration, Cleveland, OH, USA.
Cleveland Clinic · USCleveland State University · USYoungstown State University · US

Funding

The Cyclical Lower-extremity Exercise for Parkinson's TrialR01NS073717 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI ALBERTS, JAY L. · 2011 to 2023
$4.8M
NINDS NIH HHS R01 NS073717
6 · The paper itself

Abstract

backgroundIt is unknown if improvements in gait velocity following an aerobic cycling intervention are accompanied by improved gait biomechanics in individuals with Parkinson's disease (PD) or if gait abnormalities are exaggerated in response to increased velocity. Research question Can an 8-week aerobic cycling intervention elicit improvements in locomotor function in individuals with mild to moderate PD?

methodsA secondary analysis of data from a randomized clinical trial was conducted in individuals with mild to moderate idiopathic PD (N = 28). Participants were randomized to an aerobic cycling intervention (PD

resultsThe PD

Indexed as

Parkinson DiseaseBiomechanical PhenomenaExercise TherapyGaitHumansWalkingWalking SpeedBiomechanicsExerciseGaitParkinson’s disease

Identifiers

PMID36265219
PMCPMC12974380
OpenAlexW4306319912

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.