Evidence map›Paper›PMID 36265073›Full record

ArticleBMJ open2022

Burden of neurological diseases in Asia from 1990 to 2019: a systematic analysis using the Global Burden of Disease Study data.

Seungji Kang, Seuhyun Eum, Yoonkyung Chang, Ai Koyanagi, Louis Jacob, Lee Smith, Jae Il Shin, Tae-Jin Song

Abstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Article
  4. Bayesian age-period-cohort analysis and trend prediction of epilepsy disease burden in China, 1990-2021.Epileptic disorders : international epilepsy journal with videotape · 2026
    Article
  5. Diverging trends in motor neuron disease burden in China: an ageing-driven increase despite declining age-standardised rates - a GBD 2021 analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
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  8. National and subnational burden of neurological disorders in Iran, 1990 to 2021: results from the global burden of disease study 2021.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Seungji Kang *Department of Medicine, Ewha Womans University College of Medicine, Seoul, Republic of Korea.
Seuhyun Eum *Department of Medicine, Ewha Womans University College of Medicine, Seoul, Republic of Korea.
Yoonkyung Chang *Department of Neurology, Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, Republic of Korea.
Ai KoyanagiResearch and Development Unit, Parc Sanitari Sant Joan de Déu, Universitat de Barcelona, Barcelona, Spain.ORCID 0000-0002-9565-5004
Louis JacobResearch and Development Unit, Parc Sanitari Sant Joan de Déu, Universitat de Barcelona, Barcelona, Spain.ORCID 0000-0003-1071-1239
Lee SmithCentre for Health, Performance, and Wellbeing, Anglia Ruskin University, Cambridge, UK.
Jae Il ShinDepartment of Pediatrics, Yonsei University College of Medicine, Seodaemun-gu, Republic of Korea.
Tae-Jin SongDepartment of Neurology, Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Republic of Korea knstar@ewha.ac.kr.ORCID 0000-0002-9937-762X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe burden of neurological disorders is increasing worldwide, including Asia. The purpose of this study was to determine the burden of neurological disorders between 1990 and 2019 in Asia using the Global Burden of Disease (GBD) Sociodemographic Index. DESIGN, SETTING, OUTCOME AND

participantsThe GBD Study is updated every year and the most recent version provides the burden of diseases according to age, gender and region from 1990 to 2019. The burden of neurological disorders was evaluated as incidence, prevalence, mortality, disability-adjusted life-years (DALYs), years of life lost and years lived with disability.

resultsIn 2019, DALYs of neurological diseases were 64.4 million in South-East Asia (95% uncertainty interval (UI) 45.2 to 94.2) and 85.0 million in Western Pacific regions (95% UI 63.0 to 118.5). Stroke, migraine, Alzheimer's disease and other dementias had the highest DALYs in the WHO South-East Asia and WHO Western Pacific regions in 2019. DALYs of stroke, Alzheimer's disease and other dementias, Parkinson's disease, brain and central nervous system cancer, multiple sclerosis, migraine and tension-type headache increased in both regions in 2019 compared with 1990. Infectious diseases such as tetanus, meningitis and encephalitis decreased in both regions. DALYs of idiopathic epilepsy and motor neuron disease increased in the WHO South-East Asia region and decreased in the WHO Western Pacific region.

conclusionsThis study demonstrated the burden of neurological diseases in Asia. To reduce the burden of neurological diseases, strategies suitable for each country's real healthcare needs and challenges are needed; this study can serve as the cornerstone of these strategies.

Indexed as

Alzheimer DiseaseMigraine DisordersNervous System DiseasesStrokeAsiaGlobal Burden of DiseaseGlobal HealthHumansIncidencePrevalenceQuality-Adjusted Life Yearsdementiaepidemiologyneurologystroke

Identifiers

PMID36265073
PMCPMC9454052

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.