Evidence map›Paper›PMID 36264515›Full record

ArticleInsights into imaging2022

Prenatal ultrasonographic features and follow-up outcomes of 19 cases of congenital intrahepatic portosystemic venous shunts diagnosed during the foetal period.

Linlin Zhu, Haifang Wu, Xiang Cong, Shizhen Li, Qi Li, Xiangyi Dong, Guowei Tao

Open access · goldAbstract read
In one paragraph

Article in Insights into imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Article
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  6. Article
  7. A rare cause of neonatal cholestasis: congenital portosystemic shunt.Proceedings (Baylor University. Medical Center) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Linlin ZhuDepartment of Ultrasound, Qilu Hospital of Shandong University, 107 Wenhua West Road, Jinan, 250012, China.
Haifang WuDepartment of Ultrasound, Qilu Hospital of Shandong University, 107 Wenhua West Road, Jinan, 250012, China.
Xiang CongDepartment of Ultrasound, Qilu Hospital of Shandong University, 107 Wenhua West Road, Jinan, 250012, China.
Shizhen LiDepartment of Ultrasound, Qilu Hospital of Shandong University, 107 Wenhua West Road, Jinan, 250012, China.
Qi LiDepartment of Ultrasound, Qilu Hospital of Shandong University, 107 Wenhua West Road, Jinan, 250012, China.
Xiangyi DongDepartment of Ultrasound, Qilu Hospital of Shandong University, 107 Wenhua West Road, Jinan, 250012, China. dongxy907@163.com.
Guowei TaoDepartment of Ultrasound, Qilu Hospital of Shandong University, 107 Wenhua West Road, Jinan, 250012, China. taoguowei2006@163.com.
Qilu Hospital of Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate the prenatal ultrasonographic features and case characteristics of the congenital intrahepatic portosystemic venous shunt (IHPSS) diagnosed during the foetal period and analyse its prognosis.

methodsWe conducted a retrospective cohort study of patients diagnosed with IHPSS between 2016 and 2021. IHPSS was defined as an abnormal connection between the foetal intrahepatic portal and the hepatic veins.

resultsIn this study, 19 foetuses were identified, including 12 cases of single shunt and 7 cases of multiple shunts, with a gestational age of 33.8 ± 4.5 (range 25-40) weeks at diagnosis. In the single-shunt group, the origin position of the shunts was all from the left branch of the portal vein (LPV), whereas in the multiple-shunt group, the origin position of the shunts was from the LPV in six cases. Common concomitant intrauterine abnormalities of IHPSS include foetal growth restriction (47.4%) and foetal cardiac enlargement (21.1%). The postnatal manifestations of IHPSS include biochemical abnormalities (increased gamma-glutamyl transferase and bilirubin levels), neonatal hypoglycaemia, neonatal hyperammonaemia, pulmonary hypertension, multiple intrahepatic hyperechoic nodules, and cutaneous haemangiomas. Spontaneous closure of shunts occurred in ten cases, and the mean time to shunt closure was 8.1 months (1-28 months).

conclusionsMost IHPSS found during the foetal period is located in the left branch of the portal vein, and the gestational age at diagnosis is usually in the late second or third trimester. Spontaneous closure of shunts can occur in most live births, and the prognosis is good.

Indexed as

Congenital intrahepatic portosystemic venous shuntsPrenatal diagnosisPrognosisUltrasonography

Identifiers

PMID36264515
PMCPMC9584029
OpenAlexW4306868149

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.