Evidence map›Paper›PMID 36264245›Full record

ReviewNMR in biomedicine2023

Ultrashort echo time magnetic resonance imaging of the osteochondral junction.

Alecio F Lombardi, Monica Guma, Christine B Chung, Eric Y Chang, Jiang Du, Ya-Jun Ma

Abstract readReview
In one paragraph

Review in NMR in biomedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alecio F LombardiDepartment of Radiology, University of California San Diego, La Jolla, California, USA.ORCID 0000-0002-6820-1779
Monica GumaResearch Service, Veterans Affairs San Diego Healthcare System, San Diego, California, USA.
Christine B ChungDepartment of Radiology, University of California San Diego, La Jolla, California, USA.
Eric Y ChangDepartment of Radiology, University of California San Diego, La Jolla, California, USA.
Jiang DuDepartment of Radiology, University of California San Diego, La Jolla, California, USA.
Ya-Jun MaDepartment of Radiology, University of California San Diego, La Jolla, California, USA.

Funding

Ultrashort Echo Time (UTE) Magnetic Resonance Imaging of BoneR01AR068987 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2015 to 2024
$4.9M
Quantitative UTE MR Imaging: Sensitive Biomarkers for OsteoarthritisR01AR062581 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2013 to 2022
$4.1M
Resource-based Center for the study of the joint microenvironment in rheumatology (Overall Application)P30AR073761 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S · 2018 to 2022
$3.9M
Ultrashort Echo Time Magnetic Resonance Imaging of the Lumbar Intervertebral Disc.R01AR079484 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Yajun Ma · 2022 to 2026
$2.7M
Three-dimensional Ultrashort Echo Time Magnetic Resonance Imaging of EnthesesR01AR075825 · NIAMS · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI CHANG, ERIC Y · 2019 to 2023
$1.8M
Three-Dimensional UTE Magnetic Resonance Imaging of the Osteochondral JunctionR21AR075851 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MA, YAJUN · 2020 to 2021
$376k
Quantitative Measurement of Joint pH with Magnetic Resonance ImagingI01RX002604 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CHANG, ERIC Y · 2018 to 2022
–
Developing MRI Biomarkers of Myelin and Iron in Veterans with Traumatic Brain InjuryI01CX002211 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI Jiang Du · 2021 to 2026
–
Quantitative Magnetic Resonance Imaging of Human Rotator Cuff TendonI01CX001388 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CHANG, ERIC Y · 2016 to 2024
–
Ultrashort TE MR Imaging of Femorotibial CartilageI01CX000625 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CHRISTINE B CHUNG · 2012 to 2026
–
CSRD VA I01 CX000625CSRD VA I01 CX001388CSRD VA I01 CX002211NIAMS NIH HHS P30 AR073761NIAMS NIH HHS R01 AR062581NIAMS NIH HHS R01 AR068987NIAMS NIH HHS R01 AR075825NIAMS NIH HHS R01 AR079484NIAMS NIH HHS R21 AR075851RRD VA I01 RX002604
6 · The paper itself

Abstract

Osteoarthritis is a common chronic degenerative disease that causes pain and disability with increasing incidence worldwide. The osteochondral junction is a dynamic region of the joint that is associated with the early development and progression of osteoarthritis. Despite the substantial advances achieved in the imaging of cartilage and application to osteoarthritis in recent years, the osteochondral junction has received limited attention. This is primarily related to technical limitations encountered with conventional MR sequences that are relatively insensitive to short T2 tissues and the rapid signal decay that characterizes these tissues. MR sequences with ultrashort echo time (UTE) are of great interest because they can provide images of high resolution and contrast in this region. Here, we briefly review the anatomy and function of cartilage, focusing on the osteochondral junction. We also review basic concepts and recent applications of UTE MR sequences focusing on the osteochondral junction.

Indexed as

Magnetic Resonance ImagingOsteoarthritisHumansImaging, Three-DimensionalTime FactorsMRIosteochondral junctionUTE

Identifiers

PMID36264245
PMCPMC9845195

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.