Evidence map›Paper›PMID 36264064›Full record

ArticleJournal of attention disorders2023

Association Between ADHD and COVID-19 Infection and Clinical Outcomes: A Retrospective Cohort Study From Electronic Medical Records.

Kathleen P Heslin, Aminat Haruna, Regina A George, Shiyu Chen, Ishak Nobel, Kathryn B Anderson, Stephen V Faraone, Yanli Zhang-James

Registry-linked trialAbstract read
In one paragraph

Article in Journal of attention disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06042530 (Cognitive Impairment and Fatigue After Mild to Moderate COVID-19 - Relation to Biomarkers and Neuronal Network Functions), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06042530 unknown statusnot on this map

Cognitive Impairment and Fatigue After Mild to Moderate COVID-19 - Relation to Biomarkers and Neuronal Network Functions

TypeobservationalSponsorDanderyd HospitalRan2021 to 2025Enrolled100ConditionsPost COVID-19 Condition, Cognitive Impairment, Fatigue, MentalArmsNeuropsychological investigation, Optometric investigation, Magnetic Resonance Imaging, Immunological biomarkers
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kathleen P HeslinDepartment of Psychiatry, SUNY Upstate Medical University, Syracuse, NY, USA.ORCID 0000-0001-9774-0790
Aminat HarunaDepartment of Psychiatry, SUNY Upstate Medical University, Syracuse, NY, USA.
Regina A GeorgeDepartment of Psychology, University of Alabama, Tuscaloosa, AL, USA.
Shiyu ChenDepartment of Psychiatry, SUNY Upstate Medical University, Syracuse, NY, USA.
Ishak NobelDepartment of Psychiatry, SUNY Upstate Medical University, Syracuse, NY, USA.ORCID 0000-0003-2597-7013
Kathryn B AndersonInstitute for Global Health and Translational Sciences, SUNY Upstate Medical University, Syracuse, New York.
Stephen V FaraoneDepartment of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, New York.
Yanli Zhang-JamesDepartment of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, New York.ORCID 0000-0002-2104-0963

Funding

SLE Treatment with N-acetylcysteineU01AR076092 · NIAMS · UPSTATE MEDICAL UNIVERSITY · PI Michael P McDermott, Andras Perl · 2020 to 2026
$7.9M
Discoveries in ADHD genomics: Help or hype in clinical settings?R01MH116037 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI DOYLE, ALYSA E · 2019 to 2023
$4.4M
3/7 Psychiatric Genomics Consortium: Finding actionable variationU01MH109536 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CHARNEY, ALEXANDER W, HUCKINS, LAURA MARIANNE · 2016 to 2020
$2.7M
NIAMS NIH HHS U01 AR076092NIMH NIH HHS R01 MH116037NIMH NIH HHS U01 MH109536
6 · The paper itself

Abstract

objectiveThough psychiatric illnesses have been associated with increased COVID-19 infection risk, limited information exists about the relationship between ADHD and COVID-19.

methodsUsing the TriNetX COVID-19 Research Network, we examined the impact of ADHD diagnosis and treatment on COVID-19 infection rates and outcomes.

resultsADHD patients had greater risk of COVID-19 (risk ratio (RR) 1.11, 95% CI [1.09, 1.12]). Increased risk was higher in females than males, and highest among Asian and Black patients. Within 60 days after COVID-19 diagnosis, ADHD patients had lower rates of hospitalization (RR 0.91, 95% CI [0.86, 0.96]) and mechanical ventilation (RR 0.69, 95% CI [0.58, 0.83]), and a nonsignificant reduced death rate (RR 0.65, 95% CI [0.42, 1.02]). Patients who recently received ADHD medication had higher rates of COVID-19 (RR 1.13; 95% CI [1.10, 1.15]).

conclusionADHD poses increased risk for COVID-19, but may reduce risk of severe outcomes. ADHD medications modestly impacted COVID-19 risk.

Indexed as

Attention Deficit Disorder with HyperactivityCOVID-19COVID-19 TestingElectronic Health RecordsFemaleHospitalizationHumansMaleRetrospective StudiesADHDCOVID-19hospitalizationmechanical ventilationmortality

Identifiers

PMID36264064
PMCPMC9596686

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.