Evidence map›Paper›PMID 36263643›Full record

ArticleClinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology2022

DNA Methylation Pattern of Gene Promoters of MB-COMT, DRD2, and NR3C1 in Turkish Patients Diagnosed with Schizophrenia.

Hasan Mervan Aytac, Yasemin Oyaci, Mustafa Pehlivan, Sacide Pehlivan

Open access · diamondAbstract read
In one paragraph

Article in Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Hasan Mervan AytacDepartment of Psychiatry, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.ORCID https://orcid.org/0000-0002-1053-6808
Yasemin OyaciDepartment of Medical Biology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.ORCID https://orcid.org/0000-0002-1338-0087
Mustafa PehlivanDepartment of Hematology, Gaziantep University, Faculty of Medicine, Gaziantep, Turkey.ORCID https://orcid.org/0000-0002-6692-085X
Sacide PehlivanDepartment of Medical Biology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.ORCID https://orcid.org/0000-0003-1272-5845
Istanbul University · TRGaziantep University · TRIstanbul Metropolitan Municipality · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: We aim to evaluate the methylation status of membrane-bound catechol-O-methyltransferase ( Methods: A sample of 110 patients with SCZ and 100 age- and sex-matched healthy volunteers was included in the study. The interview was started by filling out data forms that included sociodemographic and clinical information. The Structured Clinical Interview for DSM-IV Axis I Disorders was used to confirming the diagnosis according to DSM-IV-TR criteria. Then the patients were evaluated with the Positive and Negative Symptoms Scale in terms of symp- tom severity. Methylation-specific polymerase chain reaction was used to determine the methylation status of Results: When we compared the percentages of Conclusion: The MB-COMT promotor,

Indexed as

COMTDNA methylationDRD2EpigeneticsNR3C1Schizophrenia

Identifiers

PMID36263643
PMCPMC9606422
OpenAlexW4306910915

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.