ArticleEpidemiology and infection2022
Transmission roles of symptomatic and asymptomatic COVID-19 cases: a modelling study.
Article in Epidemiology and infection, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Occurrence and transmission potential of asymptomatic and presymptomatic SARS-CoV-2 infections: Update of a living systematic review and meta-analysis.PLoS medicine · 2022Pooled it
- Monitoring COVID-19 occurrence in a resource-limited setting - COVID-19 sentinel surveillance in Malawi.PLOS global public health · 2026Article
- C > U mutations generate immunogenic peptides in SARS-CoV-2.Nature communications · 2025Article
- Integrated analysis for electronic health records with structured and sporadic missingness.Journal of biomedical informatics · 2025Article
- Optimization of school closures during an Omicron epidemic in Hong Kong: a modelling study.Interface focus · 2025Article
- Treatment failure and the threshold of disease extinction.Infectious Disease Modelling · 2025Article
- Interventions for SARS-CoV-2 prevention among Jailed adults: A network-based modeling analysis.Infectious Disease Modelling · 2025Article
- Development of COPMAN-Air method for high-sensitivity detection of SARS-CoV-2 in air.Scientific reports · 2025Article
- Assessing favipiravir impact on SARS-CoV-2 transmission within households: Insights from a multi-center study (FaviPrev).Journal of virus eradication · 2024Article
- SARS-CoV-2 Variants May Affect Saliva RT-PCR Assay Sensitivity.The journal of applied laboratory medicine · 2024Article
- Modeling the health impact of increasing vaccine coverage and nonpharmaceutical interventions against coronavirus disease 2019 in Ghana.Pathogens and global health · 2024Article
- COVID-19 surveillance report for Sudan, 2020 to 2021.Heliyon · 2024Article
- Article
- Looking under the lamp-post: quantifying the performance of contact tracing in the United States during the SARS-CoV-2 pandemic.BMC public health · 2024Article
- Social Mixing and Network Characteristics of COVID-19 Patients Before and After Widespread Interventions: A Population-based Study.Epidemiology and infection · 2023Article
- Clinical-Epidemiological Profile of Dental Professionals Associated with COVID-19 Infection in Southern Peru: A Cross-Sectional Study.International journal of environmental research and public health · 2022Article
Corrections and comments
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Authors and funding
14 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Coronavirus disease 2019 (COVID-19) asymptomatic cases are hard to identify, impeding transmissibility estimation. The value of COVID-19 transmissibility is worth further elucidation for key assumptions in further modelling studies. Through a population-based surveillance network, we collected data on 1342 confirmed cases with a 90-days follow-up for all asymptomatic cases. An age-stratified compartmental model containing contact information was built to estimate the transmissibility of symptomatic and asymptomatic COVID-19 cases. The difference in transmissibility of a symptomatic and asymptomatic case depended on age and was most distinct for the middle-age groups. The asymptomatic cases had a 66.7% lower transmissibility rate than symptomatic cases, and 74.1% (95% CI 65.9-80.7) of all asymptomatic cases were missed in detection. The average proportion of asymptomatic cases was 28.2% (95% CI 23.0-34.6). Simulation demonstrated that the burden of asymptomatic transmission increased as the epidemic continued and could potentially dominate total transmission. The transmissibility of asymptomatic COVID-19 cases is high and asymptomatic COVID-19 cases play a significant role in outbreaks.
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