Evidence map›Paper›PMID 36263398›Full record

ArticleEClinicalMedicine2022

Development of the PREDS score to predict in-hospital mortality of patients with Ebola virus disease under advanced supportive care: Results from the EVISTA cohort in the Democratic Republic of the Congo.

Marie Jaspard, Sabue Mulangu, Sylvain Juchet, Beatrice Serra, Ibrahim Dicko, Hans-Joeg Lang, Baweye Mayoum Baka, Gaston Musemakweli Komanda, Jeremie Muhindo Katsavara, Patricia Kabuni and 17 more

Registry-linked trialAbstract read
In one paragraph

Article in EClinicalMedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04815175, which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04815175 no registry record found
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Marie JaspardAlliance for International Medical Action (ALIMA), Dakar, Senegal.
Sabue MulanguNational Biomedical Research Institute (INRB), Kinshasa, Democratic Republic of the Congo.
Sylvain JuchetAlliance for International Medical Action (ALIMA), Dakar, Senegal.
Beatrice SerraAlliance for International Medical Action (ALIMA), Dakar, Senegal.
Ibrahim DickoAlliance for International Medical Action (ALIMA), Dakar, Senegal.
Hans-Joeg LangAlliance for International Medical Action (ALIMA), Dakar, Senegal.
Baweye Mayoum BakaAlliance for International Medical Action (ALIMA), Dakar, Senegal.
Gaston Musemakweli KomandaBeni General Hospital, North Kivu province, Democratic Republic of the Congo.
Jeremie Muhindo KatsavaraBeni General Hospital, North Kivu province, Democratic Republic of the Congo.
Patricia KabuniKinshasa University Hospital, Democratic Republic of the Congo.
Fabrice Mbika MambuNational Biomedical Research Institute (INRB), Kinshasa, Democratic Republic of the Congo.
Margaux IsnardIntensive Care Unit, Savoie Hospital, France.
Christophe VanheckeInternal Medicine Department, West Réunion Hospital, Réunion, France.
Alexia LetordSurgical Intensive Care Unit, Henri Mondor University Hospital, Créteil, France.
Ibrahima DieyeAnalysis Group Inc., Boston, MA 02199, USA.
Oscar Patterson-LombaAnalysis Group Inc., Boston, MA 02199, USA.
Olivier Tshiani MbayaNational Biomedical Research Institute (INRB), Kinshasa, Democratic Republic of the Congo.
Fiston IsekusuKinshasa University Hospital, Democratic Republic of the Congo.
Donatien MangalaKinshasa University Hospital, Democratic Republic of the Congo.
Jean Luc BiampataNational Biomedical Research Institute (INRB), Kinshasa, Democratic Republic of the Congo.
Richard KitengeMinistry of Health, National Emergency and Humanitarian Action Program, Democratic Republic of the Congo.
Moumouni KindaAlliance for International Medical Action (ALIMA), Dakar, Senegal.
Xavier AnglaretUniversity of Bordeaux, National Institute for Health and Medical Research (Inserm), Research Institute for Sustainable Development (IRD), Bordeaux Population Health Center, UMR 1219, Bordeaux, France.
Jean Jacques MuyembeNational Biomedical Research Institute (INRB), Kinshasa, Democratic Republic of the Congo.
Richard KojanAlliance for International Medical Action (ALIMA), Dakar, Senegal.
Khaled EzzedineUniversity of Bordeaux, National Institute for Health and Medical Research (Inserm), Research Institute for Sustainable Development (IRD), Bordeaux Population Health Center, UMR 1219, Bordeaux, France.
Denis MalvyUniversity of Bordeaux, National Institute for Health and Medical Research (Inserm), Research Institute for Sustainable Development (IRD), Bordeaux Population Health Center, UMR 1219, Bordeaux, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: As mortality remains high for patients with Ebola virus disease (EVD) despite new treatment options, the ability to level up the provided supportive care and to predict the risk of death is of major importance. This analysis of the EVISTA cohort aims to describe advanced supportive care provided to EVD patients in the Democratic Republic of the Congo (DRC) and to develop a simple risk score for predicting in-hospital death, called PREDS. Methods: In this prospective cohort (NCT04815175), patients were recruited during the 10 Findings: Between August 1 Interpretation: The implementation of advanced supportive care is possible for EVD patients in emergency settings. PREDS is a simple, accurate tool that could help in orienting early advanced care for at-risk patients after external validation. Funding: This study was funded by ALIMA.

Indexed as

Ebola virusIn-hospital mortalityOutcomePredictive scoreSub-Saharan AfricaSupportive care

Identifiers

PMID36263398
PMCPMC9574409

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.