Evidence map›Paper›PMID 36263376›Full record

ArticleFrontiers in molecular neuroscience2022

Analyzing the mechanisms that facilitate the subtype-specific assembly of

Catherine Choi, Joshua L Smalley, Abigail H S Lemons, Qiu Ren, Christopher E Bope, Jake S Dengler, Paul A Davies, Stephen J Moss

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. The human GABAbioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. The human GABAmicroPublication biology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Catherine ChoiDepartment of Neuroscience, Tufts University School of Medicine, Boston, MA, United States.
Joshua L SmalleyDepartment of Neuroscience, Tufts University School of Medicine, Boston, MA, United States.
Abigail H S LemonsDepartment of Neuroscience, Tufts University School of Medicine, Boston, MA, United States.
Qiu RenDepartment of Neuroscience, Tufts University School of Medicine, Boston, MA, United States.
Christopher E BopeDepartment of Neuroscience, Tufts University School of Medicine, Boston, MA, United States.
Jake S DenglerDepartment of Neuroscience, Tufts University School of Medicine, Boston, MA, United States.
Paul A DaviesDepartment of Neuroscience, Tufts University School of Medicine, Boston, MA, United States.
Stephen J MossDepartment of Neuroscience, Tufts University School of Medicine, Boston, MA, United States.
Tufts University · US

Funding

Studies on the structure of gamma-aminobutyric acid type A receptor subtypesR01MH118263 · NIMH · TUFTS UNIVERSITY BOSTON · PI MOSS, STEPHEN J · 2019 to 2023
$2.4M
Novel actions of neurosteroids on GABA (A) receptor traffickingR01NS108378 · NINDS · TUFTS UNIVERSITY BOSTON · PI DAVIES, PAUL ANDREW, MOSS, STEPHEN J · 2018 to 2022
$2.0M
Rescuing KCC2 Dysfunction in CDKL5 Deficiency Disorder to Restore GABA(A) Receptor-Mediated Hyperpolarization and Seizure Protection.R21NS126914 · NINDS · TUFTS UNIVERSITY BOSTON · PI DAVIES, PAUL ANDREW, MOSS, STEPHEN J · 2022 to 2023
$450k
B3 subunit phosphorylation determines synaptic and extrasynaptic GABAAR assemblyF31MH126542 · NIMH · TUFTS UNIVERSITY BOSTON · PI CHOI, CATHERINE · 2021 to 2022
$55k
NIMH NIH HHS F31 MH126542NIMH NIH HHS R01 MH118263NINDS NIH HHS R01 NS108378NINDS NIH HHS R21 NS126914
6 · The paper itself

Abstract

Impaired inhibitory signaling underlies the pathophysiology of many neuropsychiatric and neurodevelopmental disorders including autism spectrum disorders and epilepsy. Neuronal inhibition is regulated by synaptic and extrasynaptic

Indexed as

GABAA receptorsphosphorylationprotein purificationsubunit compositiontrafficking

Identifiers

PMID36263376
PMCPMC9574402
OpenAlexW4300166879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.