Article in Global health, epidemiology and genomics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
29 authors at 6 institutions in 2 countries.
Andrew K MaySydney Brenner Institute for Molecular Bioscience (SBIMB), Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-7045-1566
Heather SeymourSydney Brenner Institute for Molecular Bioscience (SBIMB), Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0003-3056-2170
Harriet EtheredgeWits Donald Gordon Medical Centre, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-2581-5754
Heather MaherWits Donald Gordon Medical Centre, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-3635-6346
Marta C NunesSouth African Medical Research Council, Vaccines and Infectious Diseases Analytics (VIDA) Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0003-3788-878X
Shabir A MadhiSouth African Medical Research Council, Vaccines and Infectious Diseases Analytics (VIDA) Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-7629-0636
Simiso M SokhelaEzintsha, Wits Health Consortium, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-2707-1533
W D Francois VenterEzintsha, Wits Health Consortium, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-4157-732X
Neil MartinsonPerinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-0184-5705
Firdaus NabeemeeahPerinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
Cheryl CohenDivision of Infectious Diseases, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0003-0376-2302
Jocelyn MoyesDivision of Infectious Diseases, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0001-8040-1717
Sibongile WalazaDivision of Infectious Diseases, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0001-7588-2480
Stefano TempiaDivision of Infectious Diseases, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0003-4395-347X
Jackie KleynhansDivision of Infectious Diseases, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0001-7081-6273
Anne von GottbergDivision of Infectious Diseases, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-0243-7455
Jeremy NelDepartment of Medicine, Greys Hospital, Pietermaritzburg, South Africa.ORCID 0000-0003-4115-894X
Ebrahim VariavaKlerksdorp-Tshepong Hospital Complex, Klerksdorp, and Department of Medicine, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0003-2888-789X
Stephen TollmanMRC/Wits Rural Public Health and Health Transitions Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0003-0744-7588
Kathleen KahnMRC/Wits Rural Public Health and Health Transitions Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0003-3339-3931
Kobus HerbstAfrica Health Research Institute, Durban, KwaZulu-Natal, South Africa.ORCID 0000-0002-5436-9386
Emily B WongAfrica Health Research Institute, Durban, KwaZulu-Natal, South Africa.ORCID 0000-0003-4755-5380
Caroline T TiemessenCentre for HIV and STIs, National Institute for Communicable Diseases, and Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-0991-1690
Alex van BlydensteinDivision of Pulmonology, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0003-3388-6218
Lyle MurrayDepartment of Medicine, Greys Hospital, Pietermaritzburg, South Africa.ORCID 0000-0002-3577-284X
Michelle VenterDepartment of Medicine, Greys Hospital, Pietermaritzburg, South Africa.ORCID 0000-0001-5416-7082
June FabianWits Donald Gordon Medical Centre, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0001-7130-9142
Michéle RamsaySydney Brenner Institute for Molecular Bioscience (SBIMB), Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-4156-4801
University of the Witwatersrand · ZAGrey's Hospital · ZASouth African Medical Research Council · ZAUniversity of Alabama at Birmingham · USCentre for the AIDS Programme of Research in South Africa · ZANational Health Laboratory Service · ZA
Funding
Shared Core: Biobanking, Bioinformatics and Data ManagementU54HG006938 · NHGRI · WITS HEALTH CONSORTIUM (PTY), LTD · PI RAMSAY, MICHELE MICHELE · 2012 to 2022
$12.2M
Bill & Melinda Gates Foundation INV-016202NCIRD CDC HHS U01 IP001048NHGRI NIH HHS U54 HG006938Wellcome TrustWellcome Trust 221003/Z/20/Z
6 · The paper itself
Abstract
Host genetic factors are known to modify the susceptibility, severity, and outcomes of COVID-19 and vary across populations. However, continental Africans are yet to be adequately represented in such studies despite the importance of genetic factors in understanding Africa's response to the pandemic. We describe the development of a research resource for coronavirus host genomics studies in South Africa known as COVIGen-SA-a multicollaborator strategic partnership designed to provide harmonised demographic, clinical, and genetic information specific to Black South Africans with COVID-19. Over 2,000 participants have been recruited to date. Preliminary results on 1,354 SARS-CoV-2 positive participants from four participating studies showed that 64.7% were female, 333 had severe disease, and 329 were people living with HIV. Through this resource, we aim to provide insights into host genetic factors relevant to African-ancestry populations, using both genome-wide association testing and targeted sequencing of important genomic loci. This project will promote and enhance partnerships, build skills, and develop resources needed to address the COVID-19 burden and associated risk factors in South African communities.
Indexed as
COVID-19FemaleGenome-Wide Association StudyGenomicsHumansMaleSARS-CoV-2South Africa
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Coronavirus Host Genomics Study: South Africa (COVIGen-SA). · full record | OpenQuestion