Evidence map›Paper›PMID 36263356›Full record

SynthesisFrontiers in bioengineering and biotechnology2022

The development and use of decision support framework for informing selection of select agent toxins with modelling studies to inform permissible toxin amounts.

Segaran P Pillai, Todd West, Rebecca Levinson, Julia A Fruetel, Kevin Anderson, Donna Edwards, Stephen A Morse

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trimming tiers - Motivations and means for de-risking select agents.Frontiers in bioengineering and biotechnology · 2025
    Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Segaran P PillaiOffice of the Commissioner, Food and Drug Administration, United States Department of Health and Human Services, Silver Spring, MD, United States.
Todd WestSandia National Laboratories, U.S. Department of Energy (Retired), Livermore, CA, United States.
Rebecca LevinsonSandia National Laboratories, U.S. Department of Energy, Livermore, CA, United States.
Julia A FruetelSandia National Laboratories, U.S. Department of Energy, Livermore, CA, United States.
Kevin AndersonScience and Technology Directorate, U.S. Department of Homeland Security, Washington, D.C., WA, United States.
Donna EdwardsSandia National Laboratories, U.S. Department of Energy, Livermore, CA, United States.
Stephen A MorseCenters for Disease Control and Prevention (Retired), Atlanta, GA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many countries have worked diligently to establish and implement policies and processes to regulate high consequence pathogens and toxins that could have a significant public health impact if misused. In the United States, the Antiterrorism and Effective Death Penalty Act of 1996 (

Indexed as

decision support frameworkpermissible toxin limitspublic health impactselect agents and toxinsselect toxins

Identifiers

PMID36263356
PMCPMC9573955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.