Evidence map›Paper›PMID 36263239›Full record

SynthesisInternational journal of clinical practice2022

Pit and Fissure Sealant versus Fluoride Varnish for the Prevention of Dental Caries in School Children: A Systematic Review and Meta-Analysis.

Tasneem Rashed, Nura Alkhalefa, Alaa Adam, Abdulaziz AlKheraif

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal of clinical practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07131358 (Comparison of Efficacy of Three Preventive Methods to Reduce the Incidence of Coronal Caries in Mexican Schoolchildren), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07131358 narecruitingnot on this mapstarted 2025, after this paper: background citation

Comparison of Efficacy of Three Preventive Methods to Reduce the Incidence of Coronal Caries in Mexican Schoolchildren: a Randomized Clinical Trial.

TypeinterventionalSponsorUniversidad Nacional Autonoma de MexicoRan2025 to 2027Enrolled204ConditionsCaries PreventionArmsGlass ionomer pit and fissure sealant plus fluoride varnish, Pit and fissure sealant with Giomer® technology, Fluoride varnish
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Clinical effectiveness of pit and fissure sealants in primary and permanent teeth of children and adolescents: an umbrella review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024
    Pooled it
  2. Trial
  3. Clinical performance of sealants under different humidity control conditions: a split-mouth 1-year randomized trial.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2023
    Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Oral Health Knowledge, Attitudes, and Practices among Pregnant Women in Routine Prenatal Care in South China: A Cross-Sectional Survey.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tasneem RashedDental Biomaterials Research Chair, Dental Health Department, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0003-3574-6446
Nura AlkhalefaAlfaisal University, College of Medicine, Riyadh, Saudi Arabia.
Alaa AdamKing Saud Medical City, Riyadh, Saudi Arabia.
Abdulaziz AlKheraifDental Biomaterials Research Chair, Dental Health Department, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Children's dental health has become the main concern, due to the increase in caries prevalence amongst children. Pit and fissure sealant (PFS) and fluoride varnish (FV) are effective measures for preventing dental caries. However, the clinical efficacy of these interventions when compared to one another is uncertain. The aim of the present systematic review with meta-analysis was to compare pit and fissure sealants with fluoride varnish for caries prevention of first permanent molars among schoolchildren. This is a meta-Analysis, which involves randomized control trials that compare the effectiveness of PFS with FV within 24 months of follow-up. Five databases were searched from 1990 to 2019 to identify studies published in Arabic or English language. The risk ratio (RR) and 95% confidence intervals (CIs) were calculated using a random-effects model. A total number of 4 studies were included with overall of 1249 children in both groups. Three included trial reported caries increment of first permanent molars (FPM) with 24 months of follow-up, there was no statistical significance (RR: 0.65; 95% CI 0.31 to 1.35;

Indexed as

Dental CariesPit and Fissure SealantsChildFluoridesFluorides, TopicalHumansFluoridesFluorides, TopicalPit and Fissure Sealants

Identifiers

PMID36263239
PMCPMC9553663

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.