Evidence map›Paper›PMID 36263223›Full record

ArticleFrontiers in oncology2022

Comparative analysis of extracellular vesicle isolation methods from human AML bone marrow cells and AML cell lines.

Jonas B Lang, Michèle C Buck, Jennifer Rivière, Oumaima Stambouli, Ken Sachenbacher, Purva Choudhary, Hendrik Dietz, Bernd Giebel, Florian Bassermann, Robert A J Oostendorp and 2 more

Abstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Emerging Roles of Using Small Extracellular Vesicles as an Anti-Cancer Drug.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jonas B LangDepartment of Medicine III, Technical University of Munich (TUM), Klinikum rechts der Isar, Munich, Germany.
Michèle C BuckDepartment of Medicine III, Technical University of Munich (TUM), Klinikum rechts der Isar, Munich, Germany.
Jennifer RivièreDepartment of Medicine III, Technical University of Munich (TUM), Klinikum rechts der Isar, Munich, Germany.
Oumaima StambouliInstitute for Transfusion Medicine, University Hospital Essen, Essen, Germany.
Ken SachenbacherDepartment of Physics, Technical University of Munich (TUM), Munich, Germany.
Purva ChoudharyDepartment of Medicine III, Technical University of Munich (TUM), Klinikum rechts der Isar, Munich, Germany.
Hendrik DietzDepartment of Physics, Technical University of Munich (TUM), Munich, Germany.
Bernd GiebelInstitute for Transfusion Medicine, University Hospital Essen, Essen, Germany.
Florian BassermannDepartment of Medicine III, Technical University of Munich (TUM), Klinikum rechts der Isar, Munich, Germany.
Robert A J OostendorpDepartment of Medicine III, Technical University of Munich (TUM), Klinikum rechts der Isar, Munich, Germany.
Katharina S GötzeDepartment of Medicine III, Technical University of Munich (TUM), Klinikum rechts der Isar, Munich, Germany.
Judith S HeckerDepartment of Medicine III, Technical University of Munich (TUM), Klinikum rechts der Isar, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cellular crosstalk between hematopoietic stem/progenitor cells and the bone marrow (BM) niche is vital for the development and maintenance of myeloid malignancies. These compartments can communicate

Indexed as

AMLbone marrow nicheEV isolation methodsextracellular vesiclesintercellular communication

Identifiers

PMID36263223
PMCPMC9574064

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.