SynthesisFrontiers in pediatrics2022
Maternal smoking during pregnancy and the risk of congenital urogenital malformations: A systematic review and meta-analysis.
Synthesis in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Secondhand smoke exposure and human health: an umbrella review.Nature human behaviour · 2026Pooled it
- Risks to the Unborn: An Umbrella Review on the Effects of Prenatal Maternal Stress Caused by Natural Disasters.Stress and health : journal of the International Society for the Investigation of Stress · 2025Pooled it
- Global, regional, and national burden of diseases associated with male reproduction from 1990 to 2021: a systematic analysis with forecasts to 2050.BMC public health · 2025Article
- Factors influencing late antenatal booking in Tshwane District: Pregnant women's perceptions.African journal of primary health care & family medicine · 2025Article
- Article
- Maternal and fetal risk factors for congenital anomalies of the kidney and urinary tract: a birth cohort study in urban China.Journal of nephrology · 2024Article
- Article
- Early-life exposures and long-term health: adverse gestational environments and the programming of offspring renal and vascular disease.American journal of physiology. Renal physiology · 2024Review
- Does Exposure to Ambient Air Pollution Affect Gestational Age and Newborn Weight?-A Systematic Review.Healthcare (Basel, Switzerland) · 2024Review
- Predictive factors and adverse perinatal outcomes associated with maternal smoking status.Scientific reports · 2024Article
- The epidemiology of cryptorchidism and potential risk factors, including endocrine disrupting chemicals.Frontiers in endocrinology · 2024Review
- Environmental and parental risk factors for congenital solitary functioning kidney - a case-control study.Pediatric nephrology (Berlin, Germany) · 2023Article
- Maternal Exposure to Cigarette Smoke during Pregnancy and Testicular Cancer in Offspring: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2023Review
- Parental smoking and risk of hypospadias: An updated meta-analysis of observational studies.Frontiers in pediatrics · 2023Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Investigations regarding the association between maternal smoking and specific urogenital teratogenesis exist. However, an integrated systematic review and meta-analysis studying the relationship by encompassing the whole urogenital system is essential. Objective: Even though many studies about inborn urogenital malformations have been conducted, its etiologic factors and exact pathogenesis are still unclear. Our aim is to assess the risk of congenital urogenital malformations in offspring of smoking pregnant women. Results: The meta-analysis, covering 41 case-control and 11 cohort studies, suggested that maternal smoking was associated with an increased risk of urogenital teratogenesis (odds ratio [OR] = 1.13, 95% confidence interval [CI]: 1.04-1.23, Conclusion: Our results showed that maternal smoking during pregnancy increased the risk of congenital urogenital malformations. In numerous epidemiological studies, maternal smoking during pregnancy has a significant role in fetal development. Therefore, quitting tobacco use may be an effective method for reducing the risk of congenital urogenital malformation in pregnant women.
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Registered trials
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