Evidence map›Paper›PMID 36263113›Full record

ArticleInternational journal of heart failure2021

Impact of Renal Dysfunction on Outcomes after Left Ventricular Assist Device: A Systematic Review.

Michel Ibrahim, Garly Rushler Saint Croix, Spencer Lacy, Sandra Chaparro

Abstract read
In one paragraph

Article in International journal of heart failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Renal Dysfunction in Patients with Left Ventricular Assist Device.Methodist DeBakey cardiovascular journal · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michel IbrahimDivision of Cardiovascular Medicine, Department of Medicine, Boston University Medical Center, Boston University School of Medicine, Boston, MA, USA.ORCID https://orcid.org/0000-0001-9624-0698
Garly Rushler Saint CroixDivision of Cardiology at Mount Sinai Medical Center, Columbia University, Miami Beach, FL, USA.ORCID https://orcid.org/0000-0003-1538-5567
Spencer LacyDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID https://orcid.org/0000-0002-6909-9139
Sandra ChaparroDepartment of Medicine, Baptist Health South F1orida, Miami, FL, USA.ORCID https://orcid.org/0000-0003-2472-2641

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: Renal dysfunction is a common comorbidity in patients with advanced heart failure who may benefit from left ventricular assist device (LVAD) therapy. The effect of preoperative renal dysfunction on clinical outcomes after LVAD implantation remains uncertain. We conducted a systematic review and meta-analysis to compare outcomes post-LVAD in patients with and without renal dysfunction. Methods: PubMed, MEDLINE, and Embase databases were searched for studies comparing outcomes in patients with and without renal dysfunction who underwent LVAD implantation for advanced heart failure. The primary outcome of all-cause mortality was reported as random effects risk ratio (RR) with 95% confidence interval (CI). Results: Our search yielded 5,229 potentially eligible studies. We included 7 studies reporting on 26,652 patients. Patients with renal dysfunction (glomerular filtration rate [GFR] <60 mL/min/1.73 m Conclusions: Patients with renal dysfunction have increased mortality after LVAD implantation when compared to patients with normal renal function. GFR can be used to risk stratify patients and guide decision making prior to LVAD therapy.

Indexed as

Chronic kidney diseaseHeart-assist devicesLeft ventricle assist deviceLVADVentricular assist device

Identifiers

PMID36263113
PMCPMC9536719

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.