ArticleInternational journal of heart failure2022
Body Mass Index, Muscle Mass, and All-Cause Mortality in Patients With Acute Heart Failure: The Obesity Paradox Revisited.
Article in International journal of heart failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Obesity paradox in heart failure with and without diabetes mellitus: a retrospective cohort study : Obesity paradox and DM in HF.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- The Heart's Hidden Influencer: Epicardial Adipose Tissue in the Pathogenesis of Heart Failure.Cardiology discovery · 2026Review
- From China's Multicenter Prospective Cohort: Right Ventricular Afterload and Prognosis in Hospitalized Patients with Acute Exacerbation of COPD.International journal of chronic obstructive pulmonary disease · 2026Article
- The intersection of obesity and acute heart failure: cardiac structure and function and congestion across BMI categories.European heart journal. Acute cardiovascular care · 2025Article
- The Prognostic Significance of the Pan-Immune-Inflammation Value in Patients with Heart Failure with Reduced Ejection Fraction.Diagnostics (Basel, Switzerland) · 2025Article
- Obesity and heart failure with preserved ejection fraction: focus on new drugs and future direction in medical treatment.The Korean journal of internal medicine · 2025Review
- Obesity, Metabolic Syndrome, and Obesity Paradox in Heart Failure: A Critical Evaluation.Current heart failure reports · 2024Review
- Temporal Trends in Clinical Characteristics and Outcomes for Peripartum Cardiomyopathy: The Nationwide Multicenter Registry Over 20 Years.Journal of the American Heart Association · 2024Article
- Epicardial Adipose Tissue and Heart Failure, Friend or Foe?Diabetes & metabolism journal · 2024Review
- Prediction of longitudinal clinical outcomes after acute myocardial infarction using a dynamic machine learning algorithm.Frontiers in cardiovascular medicine · 2024Article
- A synergistic impact of body mass index and gamma gap on heart failure and mortality rate among older patients with coronary artery disease: a prospective study with 10-year follow-up.Nutrition & diabetes · 2023Article
- The Obesity Paradox: An Epiphenomenon vs. A Clue for the Hidden Pathophysiology of Adiposity.Korean circulation journal · 2023Article
- Novel Insights Into the Pathogenesis of Obesity-Related High Output Heart Failure From Gene Expression Profiling.International journal of heart failure · 2023Article
- Obesity-related hypertension and chronic kidney disease: from evaluation to management.Kidney research and clinical practice · 2023Article
- Lifestyle Modification in Heart Failure Management: Are We Using Evidence-Based Recommendations in Real World Practice?International journal of heart failure · 2023Review
- Relationship between BMI and prognosis of chronic heart failure outpatients in Vietnam: a single-center study.Frontiers in nutrition · 2023Article
- The Paradox in Defining Obesity in Patients With Heart Failure.International journal of heart failure · 2022Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Objectives: Lower body mass index (BMI) is considered a poor prognostic factor in patients with heart failure (HF). We aimed to investigate the clinical impact of BMI on the risk of mortality in patients with acute HF (AHF) across various phenotypes. Methods: We retrospectively identified 4,146 registry patients with AHF and BMI data. The study population was categorized according to the WHO Asia-Pacific BMI classification: BMI <18.5 kg/m Results: During a median follow-up of 32 months, 1,732 patients (41.8%) died. Compared to patients with obesity II, those with overweight, ideal BMI or underweight status had a higher risk of mortality (overweight: hazard ratio [HR], 1.606; 95% confidence interval [CI], 1.016-2.539; p=0.042) (ideal BMI: HR, 1.744; 95% CI, 1.112-2.734; p=0.015) (underweight: HR, 2.729; 95% CI, 1.686-4.417; p<0.001). Higher risk of mortality among patients with lower BMI was observed regardless of age, sex, hypertension, diabetes, ischemic heart disease, atrial fibrillation, and HF phenotype. Furthermore, low muscle index (total muscle mass/height Conclusions: A lower BMI is associated with a higher risk of mortality in patients with AHF. This obesity paradox is observed in AHF regardless of comorbidities and HF phenotype.
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