Evidence map›Paper›PMID 36263081›Full record

ArticleInternational journal of heart failure2020

The Impact of Body Mass Index on the Prognostic Value of N-Terminal proB-Type Natriuretic Peptide in Patients with Heart Failure: an Analysis from the Korean Heart Failure (KorHF) Registry.

Hack-Lyoung Kim, Myung-A Kim, Sohee Oh, Dong-Ju Choi, Seongwoo Han, Eun-Seok Jeon, Myeong-Chan Cho, Jae-Joong Kim, Byung-Su Yoo, Mi-Seung Shin and 4 more

Abstract read
In one paragraph

Article in International journal of heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Effect of body mass index on N-terminal pro-brain natriuretic peptide values in patients with heart failure.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2023
    Article
  2. The First Anniversary of theInternational journal of heart failure · 2020
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hack-Lyoung KimDivision of Cardiology, Department of Internal Medicine, Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-6703-1472
Myung-A KimDivision of Cardiology, Department of Internal Medicine, Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3064-7118
Sohee OhDepartment of Biostatistics, Boramae Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-3010-448X
Dong-Ju ChoiDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.ORCID https://orcid.org/0000-0003-0146-2189
Seongwoo HanDepartment of Cardiovascular Medicine, Dongtan Sacred Heart Hospital, College of Medicine, Hallym University, Hwaseong, Korea.ORCID https://orcid.org/0000-0002-0327-5021
Eun-Seok JeonDepartment of Internal Medicine, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-9946-5611
Myeong-Chan ChoDepartment of Internal Medicine, Chungbuk National University College of Medicine, Cheongju, Korea.ORCID https://orcid.org/0000-0002-0047-0227
Jae-Joong KimDepartment of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2714-2282
Byung-Su YooDepartment of Internal Medicine, Yonsei University Wonju Christian Hospital, Wonju, Korea.ORCID https://orcid.org/0000-0002-3395-4279
Mi-Seung ShinDepartment of Internal Medicine, Gachon University Gil Hospital, Incheon, Korea.ORCID https://orcid.org/0000-0002-0273-0109
Seok-Min KangDepartment of Internal Medicine, Yonsei University Severance Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0001-9856-9227
Shung Chull ChaeDepartment of Internal Medicine, Kyungpook National University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-9871-6976
Kyu-Hyung RyuDepartment of Cardiovascular Medicine, Dongtan Sacred Heart Hospital, College of Medicine, Hallym University, Hwaseong, Korea.ORCID https://orcid.org/0000-0001-9329-2716
Korean Heart Failure Registry

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: Although an inverse correlation between the level of amino (N)-terminal pro-brain natriuretic peptide (NT-proBNP) and body mass index (BMI) has been reported, the impact of BMI on the prognostic value of NT-proBNP has not been well addressed. Methods: A total of 1,877 patients (67-year-old and 49.9% females) hospitalized for acute heart failure (HF) with documented NT-proBNP levels at baseline were included. Patients were classified into 2 groups by BMI (nonobese: BMI<23 kg/m Results: During the median follow-up of 828 days (interquartile range, 111-1,514 days), there were 595 cases of total mortality (31.7%), 600 cases of HF readmission (32.0%), and 934 cases of composite events (49.8%). In unadjusted analyses, higher NT-proBNP level was associated with all-cause mortality and composite events (all-cause mortality and HF readmission) in both patients with BMI<23 kg/m Conclusions: The prognostic value of NT-proBNP was more significant in nonobese patients than in overweight and obese patients in this HF population. BMI should be considered when NT-proBNP is used for risk estimation in HF patients.

Indexed as

Body mass indexHeart failureNT-proBNPObesityPrognosis

Identifiers

PMID36263081
PMCPMC9536733

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.