Evidence map›Paper›PMID 36263039›Full record

ArticleFrontiers in immunology2022

Fluorine labelling of therapeutic human tolerogenic dendritic cells for

Fiona Cooke, Mary Neal, Matthew J Wood, I Jolanda M de Vries, Amy E Anderson, Julie Diboll, Arthur G Pratt, James Stanway, Ioana Nicorescu, Nicholas Moyse and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Dendritic Cell-Hitchhiking In Vivo for Vaccine Delivery to Lymph Nodes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 3 countries.

Fiona CookeTranslational & Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Mary NealTranslational & Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Matthew J WoodTranslational & Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
I Jolanda M de VriesDepartment of Tumour Immunology, Radboudumc, Radboud Institute for Molecular Life Sciences, Nijmegen, Netherlands.
Amy E AndersonTranslational & Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Julie DibollTranslational & Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Arthur G PrattTranslational & Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
James StanwayTranslational & Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Ioana NicorescuTranslational & Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Nicholas MoyseNewcastle Advanced Therapies, Newcastle upon Tyne NHS Hospitals Foundation Trust, Newcastle upon Tyne, United Kingdom.
Dawn HilesNewcastle Advanced Therapies, Newcastle upon Tyne NHS Hospitals Foundation Trust, Newcastle upon Tyne, United Kingdom.
David CaulfieldNewcastle Advanced Therapies, Newcastle upon Tyne NHS Hospitals Foundation Trust, Newcastle upon Tyne, United Kingdom.
Anne M DickinsonTranslational & Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Andrew M BlamireTranslational & Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Pete ThelwallTranslational & Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
John D IsaacsTranslational & Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Catharien M U HilkensTranslational & Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Newcastle University · GBVersus Arthritis · GBNewcastle upon Tyne Hospitals NHS Foundation Trust · GBRadboud University Nijmegen · NLRush University Medical Center · US

Funding

Department of HealthMedical Research Council MR/N018915/1
6 · The paper itself

Abstract

Tolerogenic dendritic cell (tolDC) therapies aim to restore self-tolerance in patients suffering from autoimmune diseases. Phase 1 clinical trials with tolDC have shown the feasibility and safety of this approach, but have also highlighted a lack of understanding of their distribution

Indexed as

FluorineImmune ToleranceAnti-Inflammatory AgentsDendritic CellsHumansMagnetic Resonance ImagingAnti-Inflammatory AgentsFluorine111Indium19Fcell trackingMRIrheumatoid arthritistolerogenic dendritic cells

Identifiers

PMID36263039
PMCPMC9574244
OpenAlexW4300961002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.