ReviewFrontiers in cell and developmental biology2022
Native valve, prosthetic valve, and cardiac device-related infective endocarditis: A review and update on current innovative diagnostic and therapeutic strategies.
Review in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Impact of time from symptom onset to diagnosis in infective endocarditis: insights from the nationwide NIDUS registry.Infection · 2026Article
- Impacts of blood culture-negative status on outcomes of infectious endocarditis patients with nonsurgical and surgical intervention.Medicine · 2026Article
- Biofilms in clinical infection: pathophysiology, diagnosis, and the evolving therapeutic landscape.Journal of clinical microbiology · 2026Review
- 16S rRNA Metabarcoding Used to Identify the Etiology of Infective Endocarditis Agents.Sovremennye tekhnologii v meditsine · 2026Article
- Early and late outcomes after aortic valve replacement, mitral valve replacement and mitral valve plasty for native and prosthetic valve endocarditis in The Netherlands.European heart journal. Imaging methods and practice · 2026Article
- Infective Endocarditis in Special Populations: Epidemiology, Diagnostic Challenges, and Management Strategies.Cureus · 2025Review
- Candida Prosthetic Valve Endocarditis.Cureus · 2025Article
- Deciphering the Complex Relationships Between the Hemostasis System and Infective Endocarditis.Journal of clinical medicine · 2025Review
- Article
- Polymeric Heart Valves: Do They Represent a Reliable Alternative to Current Prosthetic Devices?Polymers · 2025Review
- Atopic dermatitis increases the risk of infective endocarditis in prosthetic heart valve patients - A retrospective study.JAAD international · 2025Article
- Bacterial Diversity in Native Heart Valves in Infective Endocarditis.Biomedicines · 2025Article
- Fluoroquinolones and Biofilm: A Narrative Review.Pharmaceuticals (Basel, Switzerland) · 2024Review
- The emerging challenge ofClinical microbiology reviews · 2024Review
- Emerging and Re-Emerging Pathogens in Valvular Infective Endocarditis: A Review.Pathogens (Basel, Switzerland) · 2024Review
- Biofilm antimicrobial susceptibility testing: where are we and where could we be going?Clinical microbiology reviews · 2023Review
- Review
- Novel putative biomarkers for infective endocarditis by serum proteomic analysis: a comprehensive review of literature.Annals of medicine and surgery (2012) · 2023Article
- Patients with Artificial Heart Valves.Deutsches Arzteblatt international · 2023Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infective endocarditis (IE) is a life-threatening microbial infection of native and prosthetic heart valves, endocardial surface, and/or indwelling cardiac device. Prevalence of IE is increasing and mortality has not significantly improved despite technological advances. This review provides an updated overview using recent literature on the clinical presentation, diagnosis, imaging, causative pathogens, treatment, and outcomes in native valve, prosthetic valve, and cardiac device-related IE. In addition, the experimental approaches used in IE research to improve the understanding of disease mechanisms and the current diagnostic pipelines are discussed, as well as potential innovative diagnostic and therapeutic strategies. This will ultimately help towards deriving better diagnostic tools and treatments to improve IE patient outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.