Evidence map›Paper›PMID 36262900›Full record

ArticleJournal of community hospital internal medicine perspectives2022

A Case-Control Study of Distinguishing Between Stroke Mimics and True Strokes.

Maya Gogtay, Yuvaraj Singh, Neha Varma, Aakriti Soni, Pawina Subedi, David Sommer, George M Abraham, Susan V George

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of community hospital internal medicine perspectives, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Maya GogtaySt. Vincent Hospital, Department of Internal Medicine, 123 Summer Street, Worcester, MA 01608, USA.
Yuvaraj SinghSt. Vincent Hospital, Department of Internal Medicine, 123 Summer Street, Worcester, MA 01608, USA.
Neha VarmaSt. Vincent Hospital, Department of Internal Medicine, 123 Summer Street, Worcester, MA 01608, USA.
Aakriti SoniSt. Vincent Hospital, Department of Internal Medicine, 123 Summer Street, Worcester, MA 01608, USA.
Pawina SubediSt. Vincent Hospital, Department of Internal Medicine, 123 Summer Street, Worcester, MA 01608, USA.
David SommerSt. Vincent Hospital, Department of Internal Medicine, 123 Summer Street, Worcester, MA 01608, USA.
George M AbrahamSt. Vincent Hospital, Department of Internal Medicine, 123 Summer Street, Worcester, MA 01608, USA.
Susan V GeorgeSt. Vincent Hospital, Department of Internal Medicine, 123 Summer Street, Worcester, MA 01608, USA.
Saint Vincent Hospital · USSt Vincent Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was conducted with the primary aim to distinguish patients with a true stroke versus a stroke mimic based on clinical features and imaging. We conducted a retrospective case-control study on 116 adult patients who received alteplase (tPA) to treat acute stroke at our hospital. We further analyzed 79 patients with a normal computed tomography angiography (CTA). Based on their magnetic resonance imaging (MRI) of the brain, they were divided into cases (stroke mimics) and controls (true strokes). Data were collected retrospectively by reviewing individual medical charts on the electronic medical record (EMR), including age, gender, history of stroke, seizure, hypertension, diabetes, atrial fibrillation, hyperlipidemia, presenting NIH Stroke Scale/Score, hemorrhagic conversion, history of migraine, history of depression, sidedness of symptoms and aphasia. Data were categorized to separate those who were later diagnosed to be stroke mimics by being-postictal, encephalopathic, in acute migraine, suffered post-stroke recrudescence (PSR) due to metabolic insult, or had conversion disorder when symptoms could not be attributed to any medical condition or mental illness. Of the 79 study subjects, 48 (60%) were stroke mimics. The mean age of the cohort was 68.67 years, and 46.8% of the study subjects were females. Based on the multivariate logistic regression analysis, factors associated with being a stroke mimic were older age, history of migraine, and a history of prior stroke. In conclusion, increased attention to history and clinical examination as the first step can aid in the proper diagnosis of strokes versus stroke mimics. Identifying stroke mimics early could help expedite hospital workup and prevent inadvertent investigations, reducing hospital occupancy during the ongoing COVID-19 pandemic. We could potentially avoid the administration of tPA to such patients, reducing both the cost and adverse effects of it. Every stroke can cause neurological deficits, but every deficit need not be a stroke.

Indexed as

AlteplaseMigraineNIH Stroke scoreStroke mimicsTrue stroke

Identifiers

PMID36262900
PMCPMC9533788
OpenAlexW4284975167

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.