ArticleInternational journal of ophthalmology2022
Age-related changes of lens thickness and density in different age phases.
Article in International journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Accommodative Demand and Near Addition in Early-Onset Primary Angle-Closure Disease: A Comparative Study.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Seeing through the veil: blue-light filtering and peak contrast sensitivity in pseudophakic patients.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Distribution characteristics and influencing factors of three-dimensional lens parameters in patients with age-related cataracts.BMC ophthalmology · 2026Article
- Detection of a white cataract with elevated intralenticular pressure using an optical biometer based on swept-source optical coherence tomography.Japanese journal of ophthalmology · 2026Observational
- Correlation between ocular biological parameters and cycloplegic refractive shift in pediatric myopia.International journal of ophthalmology · 2026Article
- Interocular Symmetry in Anterior Segment Parameters in Children With Intermittent Exotropia Observed by CASIA2 AS-OCT.Journal of ophthalmology · 2026Article
- Investigation of ciliary body inner diameter in Chinese myopic adults using ArcScan Insight® 100.Frontiers in medicine · 2026Article
- In Vivo Brillouin Analysis of Lens Nucleus and Cortex in Adult Myopic Eyes and Their Correlation With Accommodation.Investigative ophthalmology & visual science · 2025Article
- Distribution patterns and determinants of the lens thickness-to-anterior chamber depth ratio in cataract patients.Frontiers in medicine · 2025Article
- Brillouin Metrics of the Crystalline Lens Comparison Between Low-Medium Myopia and High Myopia.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- A Brillouin microscopy analysis of the crystalline lenses of Chinese adults with myopia.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Letter to the Editor Regarding "VIVEX: A Formula for Calculating Individual Vitreous Volume: A New Approach Towards Tailored Patient Dosing Regime in Intravitreal Therapy".Ophthalmology and therapy · 2024Article
- Functional effects of the spatial-varying lens mechanical properties in accommodation.JPhys photonics · 2024Article
- Two-Year Retrospective Study of Cataract Surgery and Schlemm Canal Hydrus Microstent in Black and Afro-Latino Patients.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- Age-related changes in geometry and transparency of human crystalline lens revealed by optical signal discontinuity zones in swept-source OCT images.Eye and vision (London, England) · 2023Article
- Astragalin attenuates diabetic cataractsInternational journal of ophthalmology · 2023Article
- Abnormal lens thickening in a child with Weill-Marchesani syndrome 4: A 3-year follow-up case report.Frontiers in medicine · 2022Article
- The effect of age on lens parameters and axial length among wide age range of Saudis: A prospective, cross-sectional study.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
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3 authors.
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Abstract
aimTo explore the changes in lens thickness and density with age.
methodsA Chinese population-based retrospective study was performed. A total of 497 individuals (490 right eyes and 495 left eyes), ranging from 3 to 69 years old were included. Lens images obtained from IOL Master 700 were used to measure lens thickness and density. Piecewise regression model was chosen to illustrate the relationship of lens thickness and density with age.
resultsThe proportion of people aged 3-18, 19-40, over 40 was 38.6%, 50.9% and 10.5% respectively. The whole lens thickness decreased with age during the first 7 years of life, kept stable from 8 to 16 years old, and then increased at the rate of about 27 µm per year. The thickness of the lens cortex and nucleus tended to decrease first and then increase with age, which was dependent on age stages. The whole lens density also decreased with age until 7 years old. The increasing rate of lens density was different in different age groups. The whole lens density increased rapidly from 7 to 22 years old and slowed down after 22 years old. Similarly, the changing tendency of lens cortical and nuclear density differed in different age phases.
conclusionBoth lens thickness and density are significantly associated with age, whereas they do not change linearly with age. Moreover, it is necessary to increase the population over 40 years old and conduct further research.
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