Evidence map›Paper›PMID 36262812›Full record

ArticleObstetric medicine2022

Termination of wanted pregnancy and suicidal ideation in hyperemesis gravidarum: A mixed methods study.

Melanie Nana, Florence Tydeman, Georgie Bevan, Harriet Boulding, Kimberley Kavanagh, Caitlin Dean, Catherine Williamson

Abstract read
In one paragraph

Article in Obstetric medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. The impact and management of hyperemesis gravidarum: Current and future perspectives.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Proximate and ultimate causes of pregnancy sickness.Evolution, medicine, and public health · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Melanie NanaDepartment of Obstetric Medicine, Guy's and St Thomas' NHS Foundation Trust, UK.ORCID https://orcid.org/0000-0002-7908-8986
Florence TydemanDepartment of Mathematics and Statistics, University of Strathclyde, UK.
Georgie BevanBritish Broadcasting Corporation; BBC East, UK.
Harriet BouldingThe Policy Institute, King's College London, UK.
Kimberley KavanaghDepartment of Mathematics and Statistics, University of Strathclyde, UK.
Caitlin DeanPregnancy Sickness Support, UK.
Catherine WilliamsonSchool of Life Course Sciences, King's College London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Difficulty accessing medication and poor patient experience have been implicated as risk factors for termination of pregnancy and suicidal ideation in women with hyperemesis gravidarum. We aimed to gain further insight into these factors in order to further inform and improve patient care. Methods: We performed a sub-analysis on quantitative data generated through a UK-wide survey of 5071 participants. A qualitative analysis of free text comments was performed using an inductive thematic approach. Results: 41.2% % of women taking prescribed medications had to actively request them. 'Extremely poor' or 'poor' experiences were described in 39.4% and 30.0% of participants in primary and secondary care respectively. Protective factors for termination of pregnancy and suicidal ideation include holistic support from family, friends and healthcare providers. Conclusion: Optimal care in hyperemesis gravidarum should incorporate timely access to pharmacotherapy, assessment of mental health, consideration of referral to specialist services and care being delivered in a compassionate manner.

Indexed as

Hyperemesis gravidarumsuicidal ideationtermination of pregnancytreatment experience

Identifiers

PMID36262812
PMCPMC9574451

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.