Evidence map›Paper›PMID 36262767›Full record

ArticleJAC-antimicrobial resistance2022

Modified reporting of positive urine cultures to reduce treatment of asymptomatic bacteriuria in long-term care facilities: a randomized controlled trial.

Zahra Rehan, Claire Pratt, Kim Babb, Brenda Filier, Laura Gilbert, Robert Wilson, Peter Daley

Abstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Antibiotic prescribing and antimicrobial stewardship in long-term care facilities: Past interventions and implementation challenges.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zahra RehanMemorial University, Room 1J421, 300 Prince Phillip Dr, A1B 3V6, St. John's, NL, Canada.
Claire PrattMemorial University, Room 1J421, 300 Prince Phillip Dr, A1B 3V6, St. John's, NL, Canada.
Kim BabbMemorial University, Room 1J421, 300 Prince Phillip Dr, A1B 3V6, St. John's, NL, Canada.
Brenda FilierEastern Health Region, St. John's, NL, Canada.
Laura GilbertPublic Health Microbiology Laboratory, St. John's, NL, Canada.
Robert WilsonQuality of Care NL, St. John's, NL, Canada.
Peter DaleyMemorial University, Room 1J421, 300 Prince Phillip Dr, A1B 3V6, St. John's, NL, Canada.ORCID https://orcid.org/0000-0001-7068-8056

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: We conducted a prospective, randomized, unblinded superiority trial of the safety and efficacy of modified reporting of positive urine cultures to improve the appropriateness of treatment for asymptomatic bacteriuria (ASB) and urinary tract infection (UTI) in long-term care facilities (LTCFs). Methods: Consecutive positive urine cultures collected from LTCF patients were randomized between standard (identification and susceptibility) or modified (without identification and susceptibility) laboratory reports. Exclusion criteria were current antibiotic treatment, neutropenia, or transfer to acute care. The diagnosis of UTI or ASB was made prospectively. Results: One hundred and sixty-nine urine cultures were considered, 100 were randomized and included in ITT analysis, and 96 were included in PP analysis. Sixty-two out of 100 (62%) patients had ASB [41/62 (66%) treated] and 38/100 (38%) had UTI [35/38 (92%) treated]. The lab was called to report the identification and susceptibility in 31/51 (61%) modified reports. The rate of appropriate treatment was higher in the modified report arm: 31/51 (61%) versus 25/49 (51%) (+10%, Conclusions: Modified reporting of urine culture improved the appropriateness of treatment by reducing treatment of ASB, but not significantly. Many LTCF prescribers requested standard urine culture reports. Modified reporting may not be suitable for LTCF implementation.

Identifiers

PMID36262767
PMCPMC9562817

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.