Evidence map›Paper›PMID 36262606›Full record

ReviewComputational intelligence and neuroscience2022

NOD1 and NOD2 Are Potential Therapeutic Targets for Cancer Immunotherapy.

Dongjie Wang

RetractedOpen access · hybridAbstract readReviewRetracted Publication
In one paragraph

Review in Computational intelligence and neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Structure-activity relationship in NOD2 agonistic muramyl dipeptides.European journal of medicinal chemistry · 2024
    Review
  2. Effects of Thyroid Powder on Tadpole (Animals : an open access journal from MDPI · 2024
    Article
  3. Article
  4. Article
  5. RIPK2: a promising target for cancer treatment.Frontiers in pharmacology · 2023
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

  • Retraction · 2023-08-09Concerns/Issues about Data · Concerns/Issues about Results and/or Conclusions · Concerns/Issues about Referencing/Attributions · Concerns/Issues about Peer Review · Investigation by Journal/Publisher · Investigation by Third Party · Paper Mill · Computer-Aided Content or Computer-Generated Content · Unreliable Results and/or Conclusions · · See also: https://pubpeer.com/publications/80791C06CDDF879CBA8F882AF044BE
  • Retracted
5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Dongjie WangDepartment of Pharmacy, Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, Henan 450003, China.ORCID https://orcid.org/0000-0001-8269-4904
Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nucleotide oligomerization domain (NOD)-like receptors (NLRs) are a group of intracellular proteins that are essential for controlling the host's innate immune response. The cytosolic nucleotide binding oligomerization domains 1 and 2 receptors (NOD1 and NOD2) are the most widely investigated NLRs. As pattern recognition receptors (PRRs), NOD1 and NOD2 may recognize and bind endogenous damage associated molecular patterns (DAMPs) and external pathogenic associated molecular patterns (PAMPs), directing the activation of inflammatory caspases through engaging the adaptor protein RIP2, which further activates the NF-

Indexed as

NeoplasmsNod1 Signaling Adaptor ProteinCaspasesHumansImmunotherapyMitogen-Activated Protein KinasesNF-kappa BNod2 Signaling Adaptor ProteinNucleotidesPathogen-Associated Molecular Pattern MoleculesReceptors, Pattern RecognitionCaspasesMitogen-Activated Protein KinasesNF-kappa BNOD1 protein, humanNod1 Signaling Adaptor ProteinNOD2 protein, humanNod2 Signaling Adaptor ProteinNucleotidesPathogen-Associated Molecular Pattern MoleculesReceptors, Pattern Recognition

Identifiers

PMID36262606
PMCPMC9576356
OpenAlexW4304128276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.