Evidence map›Paper›PMID 36262553›Full record

ReviewInternational journal of nephrology2022

Renal Denervation Influences Angiotensin II Types 1 and 2 Receptors.

Hajaralsadat Hosseini-Dastgerdi, Fatemeh Kharazmi, Ali-Asghar Pourshanazari, Mehdi Nematbakhsh

Abstract readReview
In one paragraph

Review in International journal of nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hajaralsadat Hosseini-DastgerdiWater & Electrolytes Research Center and Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID https://orcid.org/0000-0001-6419-3575
Fatemeh KharazmiWater & Electrolytes Research Center and Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID https://orcid.org/0000-0002-8188-0286
Ali-Asghar PourshanazariWater & Electrolytes Research Center and Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID https://orcid.org/0000-0003-4602-8765
Mehdi NematbakhshWater & Electrolytes Research Center and Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID https://orcid.org/0000-0002-9565-9187

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sympathetic and renin-angiotensin systems (RAS) are two critical regulatory systems in the kidney which affect renal hemodynamics and function. These two systems interact with each other so that angiotensin II (Ang II) has the presynaptic effect on the norepinephrine secretion. Another aspect of this interaction is that the sympathetic nervous system affects the function and expression of local RAS receptors, mainly Ang II receptors. Therefore, in many pathological conditions associated with an increased renal sympathetic tone, these receptors' expression changes and renal denervation can normalize these changes and improve the diseases. It seems that the renal sympathectomy can alter Ang II receptors expression and the distribution of RAS receptors in the kidneys, which influence renal functions.

Identifiers

PMID36262553
PMCPMC9576444

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.