Evidence map›Paper›PMID 36262543›Full record

ArticleJGH open : an open access journal of gastroenterology and hepatology2022

Comparison of long-term prognosis between non-obese and obese patients with non-alcoholic fatty liver disease.

Michihiro Iwaki, Takaomi Kessoku, Kosuke Tanaka, Anna Ozaki, Yuki Kasai, Atsushi Yamamoto, Kota Takahashi, Takashi Kobayashi, Asako Nogami, Yasushi Honda and 8 more

Abstract read
In one paragraph

Article in JGH open : an open access journal of gastroenterology and hepatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Michihiro IwakiDepartment of Gastroenterology and Hepatology Yokohama City University School of Medicine, Graduate School of Medicine Yokohama Japan.ORCID https://orcid.org/0000-0002-7650-0699
Takaomi KessokuDepartment of Gastroenterology and Hepatology Yokohama City University School of Medicine, Graduate School of Medicine Yokohama Japan.
Kosuke TanakaDepartment of Gastroenterology and Hepatology Yokohama City University School of Medicine, Graduate School of Medicine Yokohama Japan.
Anna OzakiDepartment of Gastroenterology and Hepatology Yokohama City University School of Medicine, Graduate School of Medicine Yokohama Japan.
Yuki KasaiDepartment of Gastroenterology and Hepatology Yokohama City University School of Medicine, Graduate School of Medicine Yokohama Japan.
Atsushi YamamotoDepartment of Gastroenterology and Hepatology Yokohama City University School of Medicine, Graduate School of Medicine Yokohama Japan.
Kota TakahashiDepartment of Gastroenterology and Hepatology Yokohama City University School of Medicine, Graduate School of Medicine Yokohama Japan.
Takashi KobayashiDepartment of Gastroenterology and Hepatology Yokohama City University School of Medicine, Graduate School of Medicine Yokohama Japan.ORCID https://orcid.org/0000-0002-7240-4851
Asako NogamiDepartment of Gastroenterology and Hepatology Yokohama City University School of Medicine, Graduate School of Medicine Yokohama Japan.ORCID https://orcid.org/0000-0002-6923-365X
Yasushi HondaDepartment of Gastroenterology and Hepatology Yokohama City University School of Medicine, Graduate School of Medicine Yokohama Japan.
Yuji OgawaDepartment of Gastroenterology National Hospital Organization Yokohama Medical Center Yokohama Japan.
Kento ImajoDepartment of Gastroenterology Shinyurigaoka General Hospital Kawasaki Japan.
Shunsuke OyamadaDepartment of Biostatistics JORTC Data Center Tokyo Japan.
Noritoshi KobayashiDepartment of Oncology Yokohama City University Hospital Yokohama Japan.
Shinichi AishimaDepartment of Pathology and Microbiology, Faculty of Medicine Saga University Saga Japan.
Satoru SaitoDepartment of Gastroenterology and Hepatology Yokohama City University School of Medicine, Graduate School of Medicine Yokohama Japan.
Atsushi NakajimaDepartment of Gastroenterology and Hepatology Yokohama City University School of Medicine, Graduate School of Medicine Yokohama Japan.
Masato YonedaDepartment of Gastroenterology and Hepatology Yokohama City University School of Medicine, Graduate School of Medicine Yokohama Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Non-alcoholic fatty liver disease (NAFLD) can progress in non-obese patients as in obese patients. Reports on long-term prognosis in non-obese NAFLD patients are controversial. Therefore, we aimed to examine the long-term prognosis of non-obese patients with NAFLD. Methods: This single-center, retrospective cohort study enrolled biopsy-proven non-obese and obese NAFLD patients between January 2002 and December 2011 and followed them up until 31 March 2021, for death and clinical events (cardiovascular and liver-related events and extrahepatic cancers). Results: Of the 223 NAFLD patients, 58 (26.0%) were non-obese. Compared with obese patients, they had a lower fibrosis stage (0.8 ± 0.80 Conclusion: Non-obese NAFLD does not necessarily have a good prognosis, and some cases have a poor prognosis such as extrahepatic cancers. Further validation is required in the future.

Indexed as

clinical eventsnon‐alcoholic fatty liver diseasenon‐obese non‐alcoholic fatty liver disease

Identifiers

PMID36262543
PMCPMC9575321

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.