Evidence map›Paper›PMID 36262318›Full record

ArticleJournal of chemical and engineering data2021

Solubility Measurements and Correlation of MBQ-167 in Neat and Binary Solvent Mixtures.

Jocelyn M Jiménez Cruz, Cornelis P Vlaar, Vilmalí López-Mejías, Torsten Stelzer

Abstract read
In one paragraph

Article in Journal of chemical and engineering data, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Polymorphism in early development: The account of MBQ-167.International journal of pharmaceutics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jocelyn M Jiménez CruzCrystallization Design Institute, Molecular Sciences Research Center, University of Puerto Rico, San Juan, Puerto Rico 00926, United States; Department of Pharmaceutical Sciences, University of Puerto Rico - Medical Sciences Campus, San Juan, Puerto Rico 00936, United States.ORCID 0000-0002-4549-1988
Cornelis P VlaarDepartment of Pharmaceutical Sciences, University of Puerto Rico - Medical Sciences Campus, San Juan, Puerto Rico 00936, United States.
Vilmalí López-MejíasCrystallization Design Institute, Molecular Sciences Research Center, University of Puerto Rico, San Juan, Puerto Rico 00926, United States; Department of Chemistry, University of Puerto Rico - Río Piedras Campus, San Juan, Puerto Rico 00931, United States.ORCID 0000-0003-2138-8414
Torsten StelzerCrystallization Design Institute, Molecular Sciences Research Center, University of Puerto Rico, San Juan, Puerto Rico 00926, United States; Department of Pharmaceutical Sciences, University of Puerto Rico - Medical Sciences Campus, San Juan, Puerto Rico 00936, United States.ORCID 0000-0003-3881-0183

Funding

Towards the Development of Novel Vav-Rac InhibitorsSC3GM116713 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI VLAAR, CORNELIS P · 2016 to 2019
$450k
NIGMS NIH HHS SC3 GM116713
6 · The paper itself

Abstract

MBQ-167 is a novel, small-molecule dual inhibitor of Rac and Cdc42, small GTPases that are involved in cytoskeletal organization, cell cycle progression, and cell migration. In an

Identifiers

PMID36262318
PMCPMC9578765

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.