ArticleFrontiers in public health2022
The impact of pharmacist-led antimicrobial stewardship program on antibiotic use in a county-level tertiary general hospital in China: A retrospective study using difference-in-differences design.
Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Effectiveness of educational interventions in improving antimicrobial dispensing by community pharmacists: a systematic review.BMC medical education · 2025Pooled it
- Tailored pharmacist-led intervention to improve adherence to Iron supplementation in premature infants: a randomized controlled trial in China.Frontiers in endocrinology · 2023Trial
- Impact of Pharmacist-Led Interventions on Patient Outcomes in Gulf Cooperation Council Countries: A Systematic Review and Meta-Analysis.Pharmacy (Basel, Switzerland) · 2026Review
- Impact of Clinical Pharmacist Intervention on Perioperative Antimicrobial Prophylaxis in Hysteroscopic Surgery: A Retrospective Study.Infection and drug resistance · 2026Article
- From Pandemic to Resistance: Addressing Multidrug-Resistant Urinary Tract Infections in the Balkans.Antibiotics (Basel, Switzerland) · 2025Review
- Development of a prediction model for antimicrobial stewardship pharmacy consultations to identify high-risk pediatric patients: a retrospective study across two centers.BMC infectious diseases · 2025Article
- Impact of an Antimicrobial Stewardship Program on Pre-Therapy Pathogen Detection Specimen Submission, Antimicrobial Use, and Resistant Pathogens: An Interrupted Time Series Analysis.Infection and drug resistance · 2025Article
- Impact of a pharmacist driven antimicrobial stewardship program on inpatient antibiotic consumption in a Chinese Tertiary Hospital: a 5-year retrospective study.Frontiers in medicine · 2025Article
- Article
- The Impact of Clinical Pharmacist-Driven Weekend Antimicrobial Stewardship Coverage at a Quaternary Hospital.Antibiotics (Basel, Switzerland) · 2024Article
- Evaluation of interventions led by pharmacists in antimicrobial stewardship programs in low- and middle-income countries: a systematic literature review.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2024Review
- The participation of clinical pharmacists in the treatment of patients with central nervous system infection can improve the effectiveness and appropriateness of anti-infective treatments: a retrospective cohort study.Frontiers in pharmacology · 2023Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Inappropriate use of antibiotics has become a major driver for the spread of antimicrobial resistance globally, particularly common in China. Antimicrobial stewardship programs are effective in optimizing antimicrobial use and decreasing the emergence of multi-drug-resistant organisms, and the pharmacist has performed a leading role in this program. Objective: To evaluate the impact of antimicrobial stewardship programs driven by pharmacists on antibiotic consumption and costs and the appropriateness of antibiotic use. Methods: A single-center retrospective quasi-experimental design was conducted in two independent hepatobiliary surgery wards and two independent respiratory wards in a county-level tertiary general hospital in Jiangsu, China. Each intervention group was served with antimicrobial stewardship programs with prescriptions audit and feedback, antibiotics restriction, education, and training. The propensity score matching method was employed to balance confounding variables between the intervention group and control group, and a difference-in-differences analysis was used to evaluate the impact of antimicrobial stewardship programs. The primary outcome was measured by scores of rationality evaluation of antibiotics. Results: The DID results demonstrated that the implementation of the antimicrobial stewardship programs was associated with a reduction in the average length of hospital stay (coefficient = -3.234, Conclusion: The result reveals that the implementation of the antimicrobial stewardship programs is effective in reducing the length of hospital stay, decreasing antibiotics consumption and costs, and improving the appropriateness of antimicrobial use such as decreasing irrational use of cephalosporins, reducing combinations, and improving timely conversion. However, great attention ought to be paid to the improper use of broad-spectrum antibiotics. The government is responsible for providing sustainable formal education for pharmacists, and more funding and staff support to promote antimicrobial stewardship programs.
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