Evidence map›Paper›PMID 36261540›Full record

ArticleCancer immunology, immunotherapy : CII2023

Taurine enhances the antitumor efficacy of PD-1 antibody by boosting CD8

Yu Ping, Jiqi Shan, Yaqing Liu, Fengsen Liu, Liuya Wang, Zhangnan Liu, Jieyao Li, Dongli Yue, Liping Wang, Xinfeng Chen and 1 more

Open access · greenAbstract read
In one paragraph

Article in Cancer immunology, immunotherapy : CII, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. In vitro effects of Taurine on Taxol-induced mitochondrial dysfunction.Proceedings of SPIE--the International Society for Optical Engineering · 2026
    Article
  15. Article
  16. Clinical implications of taurine in breast cancer.Biochemistry and biophysics reports · 2025
    Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Yu PingBiotherapy Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Jiqi ShanBiotherapy Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Yaqing LiuBiotherapy Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Fengsen LiuBiotherapy Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Liuya WangBiotherapy Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Zhangnan LiuBiotherapy Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Jieyao LiDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Dongli YueDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Liping WangDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Xinfeng ChenBiotherapy Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Yi ZhangBiotherapy Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China. yizhang@zzu.edu.cn.
First Affiliated Hospital of Zhengzhou University · CN

Funding

China Postdoctoral Science Foundation 2021M692928Excellent Youth Project for Health talents in Henan Province YXKC2020052Medical Science and Technology Project of Henan Province SBGJ202103083National Natural Science Foundation of China 81872333National Natural Science Foundation of China 82102869
6 · The paper itself

Abstract

The functional state of CD8

Indexed as

Antineoplastic AgentsLung NeoplasmsAmino AcidsAnimalsAntibodies, MonoclonalCD8-Positive T-LymphocytesCytokinesDisease Models, AnimalMiceProgrammed Cell Death 1 ReceptorTaurineTumor MicroenvironmentAmino AcidsAntibodies, MonoclonalAntineoplastic AgentsCytokinesProgrammed Cell Death 1 ReceptorTaurineAntitumor immunityCalcium signalingCD8+ T cellMAPK signalingPD-1 blockade antibodyTaurine

Identifiers

PMID36261540
PMCPMC10991389
OpenAlexW4306841768

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.