Evidence map›Paper›PMID 36261470›Full record

ArticleScientific reports2022

Comparison of two ultra-widefield color-fundus imaging devices for visualization of retinal periphery and microvascular lesions in patients with early diabetic retinopathy.

Heiko Stino, Susanna Riessland, Aleksandra Sedova, Felix Datlinger, Stefan Sacu, Ursula Schmidt-Erfurth, Andreas Pollreisz

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Heiko StinoDepartment of Ophthalmology and Optometry, Medical University of Vienna, Währinger Gürtel 18-20, E8i, 1090, Vienna, Austria.
Susanna RiesslandDepartment of Ophthalmology and Optometry, Medical University of Vienna, Währinger Gürtel 18-20, E8i, 1090, Vienna, Austria.
Aleksandra SedovaDepartment of Ophthalmology and Optometry, Medical University of Vienna, Währinger Gürtel 18-20, E8i, 1090, Vienna, Austria.
Felix DatlingerDepartment of Ophthalmology and Optometry, Medical University of Vienna, Währinger Gürtel 18-20, E8i, 1090, Vienna, Austria.
Stefan SacuDepartment of Ophthalmology and Optometry, Medical University of Vienna, Währinger Gürtel 18-20, E8i, 1090, Vienna, Austria.
Ursula Schmidt-ErfurthDepartment of Ophthalmology and Optometry, Medical University of Vienna, Währinger Gürtel 18-20, E8i, 1090, Vienna, Austria.
Andreas PollreiszDepartment of Ophthalmology and Optometry, Medical University of Vienna, Währinger Gürtel 18-20, E8i, 1090, Vienna, Austria. andreas.pollreisz@meduniwien.ac.at.
Medical University of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Comparison of two ultra-widefield (UWF) color-fundus (CF) imaging devices in diabetic patients for visualization of retinal periphery and detection of early microvascular lesions. The total gradable areas (TGA) seen on non-mydriatic CF-images of two UWF-imaging devices (Optos Daytona P200T; Zeiss Clarus 700) were compared and differences in projected area measured. Retinal periphery outside the 7 standard fields (7SF) was divided into: F3 temporal, F4 superotemporal, F5 inferotemporal, F6 superonasal, F7 inferonasal. DR stage was evaluated in the 7SF and the TGA on images of both devices and compared using Cohens κ. 67 eyes of 67 patients (52.5 ± 15.3 years) were analysed. DR stages in the 7SF were no (n = 36 Optos, n = 35 Clarus), mild (n = 16 Optos, n = 17 Clarus), and moderate DR (n = 15). Optos depicted significantly more area in F3 (median [interquartile range]; 2.41% [1.06-4.11] vs 0% [0-0], P < 0.001) and Clarus in F7 (3.29% [0-7.69] vs 0% [0-3.27], P = 0.002). In 4 eyes DR-stage was higher using Optos due to peripheral lesions not seen on the Clarus. Interrater reliability of DR-stage on both devices was almost perfect in the 7SF (κ = 0.975) and the TGA (κ = 0.855). Reliability in detecting signs of early DR is high on both devices. Clarus allowed for better visualization of the inferonasal field, Optos of the temporal field.

Indexed as

Diabetes MellitusDiabetic RetinopathyFluorescein AngiographyForecastingFundus OculiHumansReproducibility of ResultsRetina

Identifiers

PMID36261470
PMCPMC9582026
OpenAlexW4306784220

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.