ArticleNature communications2022
Supramolecular photodynamic agents for simultaneous oxidation of NADH and generation of superoxide radical.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- Engineering an Artificial Metalloenzyme for Efficient Photo-Enzymatic COAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Supramolecular Strategies for Modulating Excited-State Properties of Photosensitizers in Photodynamic Therapy.Angewandte Chemie (International ed. in English) · 2026Review
- Reprogramming Photosensitization Mechanisms for Hypoxic Tumor Therapy via Organic Photovoltaic-Inspired Heterojunctions.Angewandte Chemie (International ed. in English) · 2026Article
- Photo-Responsive Functional Hydrogels: Mechanism, Design, and Application.Chemistry, an Asian journal · 2026Review
- A photoimmune synergizing RNA interference technology for highly effective antitumor treatment.Smart molecules : open access · 2026Article
- Irreversible NADH Cleavage by a Mitochondria-Targeted Metal-Free Photoredox Sensitizer with Activity in Cancer Cells.ACS medicinal chemistry letters · 2026Article
- Unlocking Phthalonitrile-Based Type I Photosensitizer Through D-A Modulation to Promote Electron Transfer.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Rational Design of Organic Chromophores for Simultaneously Triggering Redox Imbalance and Tracking Organelles in Biological Systems Under Near-Infrared Light Irradiation.Advanced healthcare materials · 2026Article
- Substrate-free generation of photosensitizer radical-ion pairs enables multipath photoredox for hypoxia-tolerant photodynamic therapy.Light, science & applications · 2026Article
- pH-activatable brominated pentamethine cyanine dyes for imaging-guided photodynamic immunotherapy of tumors.Chemical science · 2026Article
- Self-Adaptive Charge Transfer States in Aqueous Solutions Promote Fast Intersystem Crossing in a Photosensitizer for Tumor Inhibition.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Design and synthesis of a tetraphenylethene-porphyrin hetero-faced molecular cage for photodynamic therapy.National science review · 2026Article
- Nanomedicine-powered redox homeostasis modulation: Disrupting antioxidant systems and inducing oxidative stress for precision tumor therapy.Materials today. Bio · 2026Review
- Atomic Ce sites promote a four-electron pathway of Pt as NADH oxidase mimics forChemical science · 2026Article
- Novel 2-(2'-Benzothiazolyl)-benzimidazole-Based Iridium(III) Photocatalysts Exhibit Antiproliferative Effects in 2D and 3D Cancer Cells to Bypass Hypoxia-Induced Resistance.Journal of medicinal chemistry · 2026Article
- Nanochirality-programmed type-I photosensitizer enables deep-tumor photodynamic therapy by reducing extracellular-matrix adhesion.Journal of controlled release : official journal of the Controlled Release Society · 2026Article
- A Closed-Loop Hybrid Discovery System of Type I Photosensitizers for Hypoxic Tumor Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Synthesis of porphyrin-formononetin derivatives and their anti-tumor activity studies.Molecular diversity · 2026Article
- NADH-Triggered Photogenerated Carbon Radicals as General Abstracting Agents for Synergism of Apoptosis and Ferroptosis.JACS Au · 2026Article
- Mitochondria-localized photocatalyst of biomimetic organic semiconductor nanoparticles for NIR-activatable photocatalytic immunotherapy.Science advances · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Given that Type-I photosensitizers (PSs) have hypoxia tolerance, developing general approaches to prepare Type-I PSs is of great importance, but remains a challenge. Here, we report a supramolecular strategy for the preparation of Type-I photodynamic agents, which simultaneously generate strong oxidizing cationic radicals and superoxide radicals, by introducing electron acceptors to the existing Type-II PSs. As a proof-of-concept, three electron acceptors were designed and co-assembled with a classical PS to produce quadruple hydrogen-bonded supramolecular photodynamic agents. The photo-induced electron transfer from the PS to the adjacent electron acceptor occurs efficiently, leading to the generation of a strong oxidizing PS
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