Evidence map›Paper›PMID 36261399›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2022

The Transient Receptor Potential Vanilloid 2 (TRPV2) Channel Facilitates Virus Infection Through the Ca

Yu-Yao Guo, Yue Gao, Yu-Ru Hu, Yuhan Zhao, Dexiang Jiang, Yulin Wang, Youjing Zhang, Hu Gan, Chang Xie, Zheng Liu and 3 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Transient receptor potential channels inChannels (Austin, Tex.) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Yu-Yao GuoDepartment of Gastrointestinal Surgery, College of Life Sciences, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, 430071, China.
Yue GaoDepartment of Gastrointestinal Surgery, College of Life Sciences, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, 430071, China.
Yu-Ru HuThe Institute for Advanced Studies, Wuhan University, Wuhan, 430072, China.
Yuhan ZhaoState Key Laboratory of Virology, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, 430072, China.
Dexiang JiangState Key Laboratory of Virology, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, 430072, China.
Yulin WangState Key Laboratory of Virology, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, 430072, China.
Youjing ZhangState Key Laboratory of Virology, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, 430072, China.
Hu GanDepartment of Gastrointestinal Surgery, College of Life Sciences, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, 430071, China.
Chang XieState Key Laboratory of Virology, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, 430072, China.
Zheng LiuThe Institute for Advanced Studies, Wuhan University, Wuhan, 430072, China.
Bo ZhongDepartment of Gastrointestinal Surgery, College of Life Sciences, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, 430071, China.ORCID 0000-0002-3832-2895
Zhi-Dong ZhangDepartment of Gastrointestinal Surgery, College of Life Sciences, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, 430071, China.
Jing YaoDepartment of Gastrointestinal Surgery, College of Life Sciences, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, 430071, China.
Wuhan University · CN

Funding

Fundamental Research Funds for the Central Universities 2042021kf0218Fundamental Research Funds for the Central Universities 2042022kf1187National Key Research and Development Program of China 2018TFE0204500National Key Research and Development Program of China 2018YFC1004601National Natural Science Foundation of Hubei Province 2020CFA015Natural Science Foundation of China 31830031Natural Science Foundation of China 31871174Natural Science Foundation of China 31929003Natural Science Foundation of China 31930040Natural Science Foundation of China 32070900Natural Science Foundation of China 32171147
6 · The paper itself

Abstract

The transient receptor potential vanilloid 2 (TRPV2) channel is a nonselective cation channel that has been implicated in multiple sensory processes in the nervous system. Here, it is shown that TRPV2 in myeloid cells facilitates virus penetration by promoting the tension and mobility of cell membrane through the Ca

Indexed as

Myeloid CellsVirus DiseasesAnimalsCalcium ChannelsMiceMice, KnockoutTRPV Cation ChannelsCalcium ChannelsTrpv2 protein, mouseTRPV Cation Channelsantiviral immunityCa2+ influxLrmdamyeloid cellsTRPV2virus penetration

Identifiers

PMID36261399
PMCPMC9731701
OpenAlexW4306836029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.