Evidence map›Paper›PMID 36261319›Full record

ArticleRapid communications in mass spectrometry : RCM2023

Boroxine benzaldehyde complex for pharmaceutical applications probed by electron interactions.

Joao Pereira-da-Silva, Ana Nunes, Monica Mendes, Rodrigo Rodrigues, Lucas Cornetta, Filipe Ferreira da Silva

Open access · hybridAbstract read
In one paragraph

Article in Rapid communications in mass spectrometry : RCM, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Joao Pereira-da-SilvaCEFITEC, Departamento de Física, NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica, Portugal.
Ana NunesCEFITEC, Departamento de Física, NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica, Portugal.
Monica MendesCEFITEC, Departamento de Física, NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica, Portugal.
Rodrigo RodriguesCEFITEC, Departamento de Física, NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica, Portugal.
Lucas CornettaInstituto de Física Gleb Wataghin, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil.
Filipe Ferreira da SilvaCEFITEC, Departamento de Física, NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica, Portugal.ORCID https://orcid.org/0000-0002-2182-2965
Universidade Nova de Lisboa · PTUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2020/04822-9Fundação para a Ciência e a Tecnologia PD/00193/2012Fundação para a Ciência e a Tecnologia PD/BD/14276872018Fundação para a Ciência e a Tecnologia PTDC/FIS/AQM/31215/2017Fundação para a Ciência e a Tecnologia UID/FIS/00068/2020
6 · The paper itself

Abstract

rationale2,4,6-Tris(4-formylphenyl)boroxine (TFPB) is a substituted boroxine containing a benzaldehyde molecule bonded to each boron atom. Boroxine cages are an emerging class of functional nanostructures used in host-guest chemistry, and benzaldehyde is a potential radiosensitizer. Reactions initiated by low-energy electrons with such complexes may dictate and bring new fundamental knowledge for biomedical and pharmaceutical applications.

methodsThe electron ionization properties of TFPB are investigated using a gas-phase electron-molecule crossed beam apparatus coupled with a reflectron time-of-flight mass spectrometer in an orthogonal geometry. Ionization and threshold energies are experimentally determined by mass spectra acquisition as a function of the electron energy.

resultsThe abundance of the molecular precursor cation in the mass spectrum at 70 eV is significantly lower than that of the most abundant fragment C

conclusionsAccording to these results, the TPFB properties may combine the potential radiosensitizer effect of benzaldehyde with the stability of the boroxine ring.

Indexed as

BenzaldehydesElectronsCationsPharmaceutical PreparationsbenzaldehydeBenzaldehydesCationsPharmaceutical Preparations

Identifiers

PMID36261319
PMCPMC9787961
OpenAlexW4306836256

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.