Evidence map›Paper›PMID 36260812›Full record

ReviewAnnual review of medicine2023

Gender-Affirming Care of Transgender and Gender-Diverse Youth: Current Concepts.

Janet Y Lee, Stephen M Rosenthal

Open access · hybridAbstract readReview
In one paragraph

Review in Annual review of medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
21.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Cass Review does not guide care for trans young people.The Medical journal of Australia · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Commentary: Without Values, Complexity is Reduced to Mathematics.Journal of evaluation in clinical practice · 2025
    Article
  17. Article
  18. Article
  19. Mental health of non-binary youth: a systematic review and meta-analysis.Child and adolescent psychiatry and mental health · 2024
    Review
  20. Clinical pharmacology in adolescent transgender medicine.British journal of clinical pharmacology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Janet Y LeeDivision of Pediatric Endocrinology, Department of Pediatrics, University of California, San Francisco, California, USA; email: Janet.lee@ucsf.edu, Stephen.rosenthal@ucsf.edu.
Stephen M RosenthalDivision of Pediatric Endocrinology, Department of Pediatrics, University of California, San Francisco, California, USA; email: Janet.lee@ucsf.edu, Stephen.rosenthal@ucsf.edu.
University of California, San Francisco · US

Funding

Training Program in Pediatric EndocrinologyT32DK007161 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Brian J Feldman, STEPHEN E GITELMAN · 1986 to 2026
$6.2M
NIDDK NIH HHS T32 DK007161
6 · The paper itself

Abstract

Increasing numbers of transgender and gender-diverse (TGD) youth, from early puberty through late adolescence, are seeking medical services to bring their physical sex characteristics into alignment with their gender identity-their inner sense of self as male or female or elsewhere on the gender spectrum. Numerous studies, primarily of short- and medium-term duration (up to 6 years), demonstrate the clearly beneficial-even lifesaving-mental health impact of gender-affirming medical care in TGD youth. However, there are significant gaps in knowledge and challenges to such care. Long-term safety and efficacy studies are needed to optimize medical care for TGD youth.

Indexed as

Transgender PersonsAdolescentFemaleGender IdentityHumansMaleMental Healthgender-affirming hormone treatmentgender-diverse youthgonadotropin-releasing hormone agonistspubertal blockerstransgender

Identifiers

PMID36260812
PMCPMC11045042
OpenAlexW4306832342

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.