ArticlePloS one2022
Affordability of essential medicines: The case of fluoride toothpaste in 78 countries.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 25 citations in OpenAlex.
- Fluoride Toothpaste Market Surveillance in the Dominican Republic: Quality Gaps and Policy Implications.Oral health & preventive dentistry · 2026Article
- Oral and hand hygiene practices among adolescents aged 12-17 years in 72 countries: a cross-sectional study using global school-based student health survey data (2010-2019).Frontiers in public health · 2026Article
- Temporal trends in cross-country inequalities of permanent caries burden from 1990 to 2021: a secondary analysis of the global burden of disease study 2021.BMC oral health · 2025Article
- Should we be concerned about the use of non-fluoride toothpaste? A survey study in two European countries.International journal of dental hygiene · 2025Article
- Effects of Sr/F-bioactive glass nanoparticles on pH, elemental release, dentin remineralisation, and cytotoxicity of 1.1% NaF toothpaste.Biomaterial investigations in dentistry · 2025Article
- Access to dental services and use of toothpaste with optimal fluoride content in Peruvian children.Frontiers in dental medicine · 2024Article
- Global Geographical Disparities in Untreated Caries of Permanent Teeth.Galen medical journal · 2024Review
- Cost-effectiveness of dental caries prevention strategies in South African schools.BMC oral health · 2023Article
- Next preventive strategies for oral health: evolution or revolution?Frontiers in public health · 2023Article
- Surface Accumulation of Cerium, Self-Assembling Peptide, and Fluoride on Sound Bovine Enamel.Bioengineering (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 4 countries.
Funding
Abstract
backgroundFluoride toothpaste (FT) has recently been included in the WHO Model List of Essential Medicines. Whereas it is essential for preventing dental caries, its current affordability around the globe remains unclear. This study aimed to analyse the affordability of FT in as many as possible countries worldwide, to capture the extent of variations in FT affordability between high-, middle- and low-income countries.
methodsA standardized protocol was developed to collect country-specific information about the characteristics of the cheapest available FT at a regular point of purchase. 82 members of the WHO Global Oral Health Network of Chief Dental Officers (CDOs), directors of WHO Collaborative Centres and other oral health experts collected data using mobile phone technology. In line with established methodologies to assess affordability, the Fluoride Toothpaste Affordability Ratio (FTAR) was calculated as the expenditure associated with the recommended annual consumption of FT relative to the daily wage of the lowest-paid unskilled government worker (FTAR >1 = unaffordable spending on fluoride toothpaste).
resultsThere are significant differences in the affordability of FT across 78 countries. FT was strongly affordable in high-income countries, relatively affordable in upper middle-income countries, and strongly unaffordable in lower middle-income and low-income countries. The affordability of FT across WHO Regions was dependent upon the economic mix of WHO Regions' member states.
conclusionFT is still unaffordable for many people, particularly in low-income settings. Strategies to improve the universal affordability of FT should be part of health policy decisions in order to contribute to reducing dental caries as a global public health problem.
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